NP_055058.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
135,603 Da
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 3 preproprotein
NCBI Official Synonym Full Names
ADAM metallopeptidase with thrombospondin type 1 motif 3
NCBI Official Synonym Symbols
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 3
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 3
UniProt Synonym Protein Names
Procollagen II N-proteinase; PC II-NP; Procollagen II amino propeptide-processing enzyme
UniProt Synonym Gene Names
NCBI Summary for ADAMTS3
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. [provided by RefSeq, Feb 2016]
UniProt Comments for ADAMTS3
Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens.
Research Articles on ADAMTS3
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Pathways associated with ADAMTS3 recombinant protein
Diseases associated with ADAMTS3 recombinant protein
Organs/Tissues associated with ADAMTS3 recombinant protein
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