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AKAP4 recombinant protein :: A-kinase anchor protein 4 (AKAP4) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1473940
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $135 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $255 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $420 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $665 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,090 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $1,135 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,255 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,510 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,540 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,595 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
0.5 mg (Yeast)  /  $1,745 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,270 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,280 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,635 +3 FREE 8GB USB
1 mg (Baculovirus)  /  $2,985 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A-kinase anchor protein 4 (AKAP4), Recombinant Protein

 Also Known As   

Recombinant Human A-kinase anchor protein 4 (AKAP4)

 Product Synonym Names    A-kinase anchor protein 4; AKAP-4; A-kinase anchor protein 82 kDa; AKAP 82; hAKAP82; Major sperm fibrous sheath protein; HI; Protein kinase A-anchoring protein 4; PRKA4
 Product Gene Name   

AKAP4 recombinant protein

[Similar Products]
 Product Synonym Gene Name    AKAP4; AKAP82 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    189-854aa; Full Length
 Sequence    QSPSAPPAKP PSTQRAVISP DGECSIDDLS FYVNRLSSLV IQMAHKEIKE KLEGKSKCLH HSICPSPGNK ERISPRTPAS KIASEMAYEA VELTAAEMRG TGEESREGGQ KSFLYSELSN KSKSGDKQMS QRESKEFADS ISKGLMVYAN QVASDMMVSL MKTLKVHSSG KPIPASVVLK RVLLRHTKEI VSDLIDSCMK NLHNITGVLM TDSDFVSAVK RNLFNQWKQN ATDIMEAMLK RLVSALIGEE KETKSQSLSY ASLKAGSHDP KCRNQSLEFS TMKAEMKERD KGKMKSDPCK SLTSAEKVGE HILKEGLTIW NQKQGNSCKV ATKACSNKDE KGEKINASTD SLAKDLIVSA LKLIQYHLTQ QTKGKDTCEE DCPGSTMGYM AQSTQYEKCG GGQSAKALSV KQLESHRAPG PSTCQKENQH LDSQKMDMSN IVLMLIQKLL NENPFKCEDP CEGENKCSEP RASKAASMSN RSDKAEEQCQ EHQELDCTSG MKQANGQFID KLVESVMKLC LIMAKYSNDG AALAELEEQA ASANKPNFRG TRCIHSGAMP QNYQDSLGHE VIVNNQCSTN SLQKQLQAVL QWIAASQFNV PMLYFMGDKD GQLEKLPQVS AKAAEKGYSV GGLLQEVMKF AKERQPDEAV GKVARKQLLD WLLANL
 OMIM    300185
 3D Structure    ModBase 3D Structure for Q5JQC9
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of AKAP4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for AKAP4 recombinant protein

   Major structural component of sperm fibrous sheath. Plays a role in sperm motility.
 Product Categories/Family for AKAP4 recombinant protein    Signal Transduction
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 SDS-PAGE of AKAP4 recombinant protein    AKAP4 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for AKAP4. It may not necessarily be applicable to this product.
 NCBI GI #    21493037
 NCBI GeneID    8852
 NCBI Accession #    NP_003877.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003886.2 [Other Products]
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 UniProt Primary Accession #    Q5JQC9 [Other Products]
 UniProt Secondary Accession #    O60904; O95246; Q5JQD1; Q5JQD2; Q5JQD3; A0AV85 [Other Products]
 UniProt Related Accession #    Q5JQC9 [Other Products]
 Molecular Weight    93,445 Da
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 NCBI Official Full Name    A-kinase anchor protein 4 isoform 1
 NCBI Official Synonym Full Names    A kinase (PRKA) anchor protein 4
 NCBI Official Symbol    AKAP4 [Similar Products]
 NCBI Official Synonym Symbols   
HI; p82; CT99; FSC1; PRKA4; AKAP-4; AKAP82; AKAP 82; hAKAP82
[Similar Products]
 NCBI Protein Information    A-kinase anchor protein 4; testis-specific gene HI; cancer/testis antigen 99; A-kinase anchor protein 82 kDa; major sperm fibrous sheath protein; protein kinase A anchoring protein 4; protein kinase A-anchoring protein 4
 UniProt Protein Name    A-kinase anchor protein 4
 UniProt Synonym Protein Names   
A-kinase anchor protein 82 kDa; AKAP 82; hAKAP82; Major sperm fibrous sheath protein; HI; Protein kinase A-anchoring protein 4; PRKA4
 Protein Family    A-kinase anchor protein
 UniProt Gene Name    AKAP4 [Similar Products]
 UniProt Synonym Gene Names    AKAP-4; AKAP 82; hAKAP82; HI; PRKA4 [Similar Products]
 UniProt Entry Name    AKAP4_HUMAN
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 NCBI Summary for AKAP4    The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AKAP4    AKAP4: Major structural component of sperm fibrous sheath. Plays a role in sperm motility. Belongs to the AKAP110 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cancer Testis Antigen (CTA); Adaptor/scaffold

Chromosomal Location of Human Ortholog: Xp11.2

Cellular Component: cytoskeleton; perinuclear region of cytoplasm; cytoplasm; nucleus; Z disc; cAMP-dependent protein kinase complex

Molecular Function: protein kinase A binding

Biological Process: sperm motility; protein localization; cell projection organization and biogenesis; single fertilization; transmembrane receptor protein serine/threonine kinase signaling pathway; signal transduction; cell motility
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 Research Articles on AKAP4    1. The putative role of AKAP4 in early tumorigenesis is implicated as a biomarker and immunotherapeutic target for cervical cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AKAP4 recombinant proteinPathways associated with AKAP4 recombinant protein
 Reference Product  PubMed Publications
 AKAP3 recombinant protein  >13 publications with AKAP4 and AKAP3
 Products by Pathway  Pathway Diagram
 G Protein Signaling Pathways antibodies  G Protein Signaling Pathways Diagram
Diseases associated with AKAP4 recombinant proteinOrgans/Tissues associated with AKAP4 recombinant protein
 Disease Name  Pubmed Publications
 Genital Diseases, Male Antibodies  >19 publications with AKAP4 and Genital Diseases, Male
 Infertility, Male Antibodies  >16 publications with AKAP4 and Infertility, Male
 Immune System Diseases Antibodies  >2 publications with AKAP4 and Immune System Diseases
 Gonadal Disorders Antibodies  >1 publications with AKAP4 and Gonadal Disorders
 Oligospermia Antibodies  >1 publications with AKAP4 and Oligospermia
 Infertility, Female Antibodies  >1 publications with AKAP4 and Infertility, Female
 Prostatic Diseases Antibodies  >1 publications with AKAP4 and Prostatic Diseases
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >15 publications with AKAP4 and Testis
 Brain Antibodies  >4 publications with AKAP4 and Brain
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