Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow Akap5  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • 14-3-3 protein gamma-B (ywhag-b) Recombinant Protein
 • Outer-membrane lipoprotein carrier protein (lolA) Recombinant Protein
 • 3-hydroxy-3-methylglutaryl- coenzyme A reductase (HMGCR) Recombinant Protein
 • Stress response protein yvgO (yvgO) Recombinant Protein
 • APPL1 Peptide
 • Cross linked N terminal Telopeptides of type I collagen (NTx... ELISA Kit
 • TETANUS TOXIN (tetX) Purified Protein
 • Amoxycillin, Ampicillin and Penicillin Antibody
 • PRKCDBP Peptide
 • Galectin-9 (LGALS9) Recombinant Protein
 • Thymosin alpha1 (TMSalpha1) ELISA Kit
 • solute carrier family 39 (zinc transporter) , member 14 (SLC... ELISA Kit
 • CMRF35-like molecule 8 (CD300A) ELISA Kit
 • Monocyte Chemotactic Protein 3 (MCP-3) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

Akap5 recombinant protein :: A-kinase anchor protein 5 (Akap5) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1039149 Akap5 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $1,205 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,320 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,570 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,590 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,635 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,675 +2 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,755 +2 FREE 8GB USB
0.5 mg (Yeast)  /  $1,845 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,360 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,390 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,500 +3 FREE 8GB USB
1 mg (Yeast)  /  $2,795 +3 FREE 8GB USB
1 mg (Baculovirus)  /  $3,125 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A-kinase anchor protein 5 (Akap5), Recombinant Protein

 Also Known As   

Recombinant Mouse A-kinase anchor protein 5 (Akap5)

 Product Synonym Names    A-kinase anchor protein 5; AKAP-5; A-kinase anchor protein 150 kDa; AKAP 150; P150; cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein
 Product Gene Name   

Akap5 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Akap5; Akap150 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    1-745aa; full length protein
 Sequence    METSVSEIQV ETKDEKGPVA ASPQKERQER KTATLCFKRR KKANKTKPKA GSRTAEETKK HTPEAGGSGQ RQPAGAWASI KGLVTHRKRS EPAKKQKPPE AEVQPEDGAL PKKKAKSRLK FPCLRFSRGA KRSRHSKLTE DSGYVRVQGE ADDLEIKAQT QPDDQAIQAG STQGLQEGVL VRDGKKSQES HISNSVTSGE NVIAIELELE NKSSAIQMGT PELEKETKVI TEKPSVQTQR ASLLESSAAG SPRSVTSAAP PSPATTHQHS LEEPSNGIRE SAPSGKDDRR KTAAEEKKSG ETALGQAEEA AVGQADKRAL SQAGEATAGH PEEATVIQAE SQAKEGKLSQ AEETTVAQAK ETVLSQAKEG ELSQAKKATV GQAEEATIDH TEKVTVDQAE ETTVGQAEEA TVGQAGEAIL SQAKEATVVG QAEEATVDRA EEATVGQAEE ATVGHTEKVT VDQAEEATVG QAEEATVGQA EEATVDWAEK PTVGQAEEAT VGQAEEATVG HTEKVTVDQA EEATVGQAEE ATVGHTEKVT VDHAEEATVG QAEEATVGQA EKVTVDHAEE ATVGQAEEAT VGQAEKVTVD HAEEATVGQA EEATVGQAEK VTVDQAEEPT VDQAEEAISS HAPDLKENGI DTEKPRSEES KRMEPIAIII TDTEISEFDV KKSKNVPKQF LISMENEQVG VFANDSDFEG RTSEQYETLL IETASSLVKN AIELSVEQLV NEMVSEDNQI NTLFQ
 3D Structure    ModBase 3D Structure for D3YVF0
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Mus musculus (Mouse)
Section Bar
 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Akap5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for Akap5. It may not necessarily be applicable to this product.
 NCBI GI #    158187517
 NCBI GeneID    238276
 NCBI Accession #    NP_001094941.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001101471.1 [Other Products]
Section Bar
 UniProt Primary Accession #    D3YVF0 [Other Products]
 UniProt Secondary Accession #    D3Z5C9 [Other Products]
 UniProt Related Accession #    D3YVF0 [Other Products]
 Molecular Weight    79,397 Da
Table BarTOPTable Bar
 NCBI Official Full Name    A-kinase anchor protein 5
 NCBI Official Synonym Full Names    A kinase (PRKA) anchor protein 5
 NCBI Official Symbol    Akap5 [Similar Products]
 NCBI Official Synonym Symbols   
P150; Gm258; AKAP-5; AKAP150; AKAP 150; BB098886; 3526401B18Rik
[Similar Products]
 NCBI Protein Information    A-kinase anchor protein 5; A-kinase anchor protein 150 kDa; cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein
 UniProt Protein Name    A-kinase anchor protein 5
 UniProt Synonym Protein Names   
A-kinase anchor protein 150 kDa; AKAP 150; P150; cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein
 Protein Family    A-kinase anchor protein
 UniProt Gene Name    Akap5 [Similar Products]
 UniProt Synonym Gene Names    Akap150; AKAP-5; AKAP 150; P150 [Similar Products]
 UniProt Entry Name    AKAP5_MOUSE
Section Bar
 UniProt Comments for Akap5    AKAP5: May anchor the PKA protein to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors. Association with to the beta2-adrenergic receptor (beta2-AR) not only regulates beta2-AR signaling pathway, but also the activation by PKA by switching off the beta2-AR signaling cascade. Binding protein for dimer of the RII-beta regulatory subunit of cAMP-dependent protein kinase (PKA) and also for the protein kinase C (PKC) and the phosphatase calcineurin (PP2B). Each enzyme is inhibited when bound to the anchoring protein. Also binds the beta2-adrenergic receptor. Part of a complex containing AKAP5, ADCY5, ADCY6 AND PDE4C. Interacts with ADCY8, and enhances its phosphorylation at lipid rafts. Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary.

Protein type: Adaptor/scaffold

Cellular Component: filopodium membrane; protein complex; basolateral plasma membrane; postsynaptic density; dendritic spine; asymmetric synapse; cytoskeleton; membrane; cell soma; perinuclear region of cytoplasm; cytoplasm; plasma membrane; dendritic shaft

Molecular Function: calmodulin binding; protein domain specific binding; protein binding; G-protein-coupled receptor binding; cadherin binding; protein complex binding; GABA receptor binding; actin binding; kinase binding; protein kinase binding; protein phosphatase 2B binding; adenylate cyclase binding

Biological Process: cellular protein complex disassembly; positive regulation of NFAT protein import into nucleus; negative regulation of potassium ion transport; positive regulation of cAMP biosynthetic process; negative regulation of adenylate cyclase activity; positive regulation of adenylate cyclase activity; positive regulation of protein amino acid phosphorylation; positive regulation of dendrite morphogenesis; signal transduction; negative regulation of ion transport; protein targeting
Table BarTOPTable Bar
 Research Articles on Akap5    1. Our results support a model whereby subcellular anchoring of CaN by AKAP150 is a key molecular determinant of vascular BKCa channel remodeling, which contributes to vasoconstriction during diabetes mellitus.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with Akap5 recombinant proteinDiseases associated with Akap5 recombinant protein
 Products by Pathway  Pathway Diagram
 G Protein Signaling Pathways antibodies  G Protein Signaling Pathways Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >14 publications with Akap5 and Nervous System Diseases
 Hypertrophy Antibodies  >5 publications with Akap5 and Hypertrophy
 Inflammation Antibodies  >4 publications with Akap5 and Inflammation
 Cardiomegaly Antibodies  >4 publications with Akap5 and Cardiomegaly
 Seizures Antibodies  >4 publications with Akap5 and Seizures
 Heart Defects, Congenital Antibodies  >2 publications with Akap5 and Heart Defects, Congenital
 Congenital Abnormalities Antibodies  >2 publications with Akap5 and Congenital Abnormalities
 Disease Models, Animal Antibodies  >2 publications with Akap5 and Disease Models, Animal
 Memory Disorders Antibodies  >2 publications with Akap5 and Memory Disorders
 Hyperplasia Antibodies  >1 publications with Akap5 and Hyperplasia
Organs/Tissues associated with Akap5 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >63 publications with Akap5 and Brain
 Pancreas Antibodies  >3 publications with Akap5 and Pancreas
 Sympathetic Ganglion Antibodies  >2 publications with Akap5 and Sympathetic Ganglion
 Lung Antibodies  >2 publications with Akap5 and Lung
 Embryonic Tissue Antibodies  >1 publications with Akap5 and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions