NP_004833.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,518 Da
NCBI Official Full Name
A-kinase anchoring protein 7 isoform alpha
NCBI Official Synonym Full Names
A-kinase anchoring protein 7
NCBI Protein Information
A-kinase anchor protein 7; A-kinase anchoring protein 7
UniProt Protein Name
A-kinase anchor protein 7 isoforms alpha and beta
UniProt Synonym Protein Names
A-kinase anchor protein 18 kDa; AKAP 18; Protein kinase A-anchoring protein 7 isoforms alpha/beta; PRKA7 isoforms alpha/beta
UniProt Synonym Gene Names
AKAP15; AKAP18; AKAP-7 isoforms alpha and beta; AKAP 18; PRKA7 isoforms alpha/beta [Similar Products]
NCBI Summary for AKAP7
This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Apr 2011]
UniProt Comments for AKAP7
Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.
Research Articles on AKAP7
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Products associated with AKAP7 recombinant protein
Pathways associated with AKAP7 recombinant protein
Diseases associated with AKAP7 recombinant protein
Organs/Tissues associated with AKAP7 recombinant protein
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