NP_001090.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,443 Da
NCBI Official Full Name
prostatic acid phosphatase isoform PAP
NCBI Official Synonym Full Names
acid phosphatase, prostate
NCBI Protein Information
prostatic acid phosphatase
UniProt Protein Name
Prostatic acid phosphatase
UniProt Synonym Protein Names
5'-nucleotidase (EC:3.1.3.5); 5'-NT
UniProt Synonym Gene Names
UniProt Entry Name
PPAP_HUMAN
NCBI Summary for ACPP
This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]
UniProt Comments for ACPP
A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.
Research Articles on ACPP
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Disclaimer
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Products associated with ACPP recombinant protein
Pathways associated with ACPP recombinant protein
Diseases associated with ACPP recombinant protein
Organs/Tissues associated with ACPP recombinant protein
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