Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow ARFGAP1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Interleukin 5 (IL-5) ELISA Kit
 • TNFSF13 Recombinant Protein
 • AChE (Acetylcholinesterase) CLIA Kit
 • CBS Antibody
 • Angiotensin (1-7) (ANG (1-7) ) ELISA Kit
 • Prolactin (PRL) Antibody
 • a-Ethyl-N-formyl-N-methylpy ridinemethaneamine Biochemical
 • DNA Ligase 4 (LIG4) Antibody
 • Hyaluronic Acid (HA) ELISA Kit
 • Vaspin (SERPINA12) Recombinant Protein
 • PSCA Antibody
 • alpha2-Macroglobulin (alpha2-MG) ELISA Kit
 • Glial Fibrillary Acidic Protein (GFAP) ELISA Kit
 • G-CSF (CSF3) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

ARFGAP1 recombinant protein :: ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1301288 ARFGAP1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $820 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $925 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,055 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,100 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,210 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,240 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,300 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,335 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,405 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,720 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,920 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,970 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,140 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,530 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1), Recombinant Protein

 Also Known As   

Recombinant Human ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1)

 Product Synonym Names    ADP-ribosylation factor GTPase-activating protein 1; ARF GAP 1; ADP-ribosylation factor 1 GTPase-activating protein; ARF1 GAP; ARF1-directed GTPase-activating protein
 Product Gene Name   

ARFGAP1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    ARFGAP1; ARF1GAP [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    1-406aa; full length protein
 Sequence    MASPRTRKVL KEVRVQDENN VCFECGAFNP QWVSVTYGIW ICLECSGRHR GLGVHLSFVR SVTMDKWKDI ELEKMKAGGN AKFREFLESQ EDYDPCWSLQ EKYNSRAAAL FRDKVVALAE GREWSLESSP AQNWTPPQPR TLPSMVHRVS GQPQSVTASS DKAFEDWLND DLGSYQGAQG NRYVGFGNTP PPQKKEDDFL NNAMSSLYSG WSSFTTGASR FASAAKEGAT KFGSQASQKA SELGHSLNEN VLKPAQEKVK EGKIFDDVSS GVSQLASKVQ GVGSKGWRDV TTFFSGKAEG PLDSPSEGHS YQNSGLDHFQ NSNIDQSFWE TFGSAEPTKT RKSPSSDSWT CADTSTERRS SDSWEVWGSA STNRNSNSDG GEGGEGTKKA VPPAVPTDDG WDNQNW
 OMIM    608377
 3D Structure    ModBase 3D Structure for Q8N6T3
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Homo sapiens (Human)
Section Bar
 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ARFGAP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for ARFGAP1 recombinant protein

   This protein is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for ARFGAP1. It may not necessarily be applicable to this product.
 NCBI GI #    527498254
 NCBI GeneID    55738
 NCBI Accession #    NP_001268411.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001281482.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q8N6T3 [Other Products]
 UniProt Secondary Accession #    Q6PK71; Q96KC4; Q96T02; Q9NSU3; Q9NVF6; Q9UIL0; B7Z3U0; B7Z8H8; B7ZBI3; E1P5I9; E7EV62 [Other Products]
 UniProt Related Accession #    Q8N6T3 [Other Products]
 Molecular Weight    39,705 Da
Table BarTOPTable Bar
 NCBI Official Full Name    ADP-ribosylation factor GTPase-activating protein 1 isoform c
 NCBI Official Synonym Full Names    ADP-ribosylation factor GTPase activating protein 1
 NCBI Official Symbol    ARFGAP1 [Similar Products]
 NCBI Official Synonym Symbols   
ARF1GAP; HRIHFB2281
[Similar Products]
 NCBI Protein Information    ADP-ribosylation factor GTPase-activating protein 1; ARF1-directed GTPase-activating protein
 UniProt Protein Name    ADP-ribosylation factor GTPase-activating protein 1
 UniProt Synonym Protein Names   
ADP-ribosylation factor 1 GTPase-activating protein; ARF1 GAP; ARF1-directed GTPase-activating protein
 Protein Family    ADP-ribosylation factor GTPase-activating protein
 UniProt Gene Name    ARFGAP1 [Similar Products]
 UniProt Synonym Gene Names    ARF1GAP; ARF GAP 1; ARF1 GAP [Similar Products]
 UniProt Entry Name    ARFG1_HUMAN
Section Bar
 NCBI Summary for ARFGAP1    The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Section Bar
 UniProt Comments for ARFGAP1    ARF GAP1: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; GAPs; GAPs, ARF

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: synapse; cytosol

Molecular Function: protein binding; zinc ion binding; GTPase activator activity

Biological Process: protein transport; COPI coating of Golgi vesicle; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; unfolded protein response; retrograde vesicle-mediated transport, Golgi to ER; positive regulation of GTPase activity
Table BarTOPTable Bar
 Research Articles on ARFGAP1    1. ARFGAP1 is a host factor for Hepatitis C Virus RNA replication, and is hijacked by HCV NS5A to remove COPI cargo Sac1 from the site of HCV replication to maintain high levels of PI4P.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with ARFGAP1 recombinant proteinPathways associated with ARFGAP1 recombinant protein
 Reference Product  PubMed Publications
 ARF1 recombinant protein  >30 publications with ARFGAP1 and ARF1
 Products by Pathway  Pathway Diagram
 Activation Of Chaperone Genes By XBP1(S) Pathway antibodies  Activation Of Chaperone Genes By XBP1(S) Pathway Diagram
 Activation Of Chaperones By IRE1alpha Pathway antibodies  Activation Of Chaperones By IRE1alpha Pathway Diagram
 Arf1 Pathway antibodies  Arf1 Pathway Diagram
 COPI Mediated Transport Pathway antibodies  COPI Mediated Transport Pathway Diagram
 Diabetes Pathways antibodies  Diabetes Pathways Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Golgi To ER Retrograde Transport Pathway antibodies  Golgi To ER Retrograde Transport Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
Diseases associated with ARFGAP1 recombinant proteinOrgans/Tissues associated with ARFGAP1 recombinant protein
 Disease Name  Pubmed Publications
 Neurologic Manifestations Antibodies  >2 publications with ARFGAP1 and Neurologic Manifestations
 Neurobehavioral Manifestations Antibodies  >2 publications with ARFGAP1 and Neurobehavioral Manifestations
 Nervous System Diseases Antibodies  >2 publications with ARFGAP1 and Nervous System Diseases
 Brain Diseases Antibodies  >1 publications with ARFGAP1 and Brain Diseases
 Seizures Antibodies  >1 publications with ARFGAP1 and Seizures
 Developmental Disabilities Antibodies  >1 publications with ARFGAP1 and Developmental Disabilities
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with ARFGAP1 and Brain
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions