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ARL2BP recombinant protein :: ADP-ribosylation factor-like protein 2-binding protein Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS717212
SDS-PAGE
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $220 +1 FREE 8GB USB
0.2 mg  /  $295 +1 FREE 8GB USB
0.5 mg  /  $580 +1 FREE 8GB USB
1 mg  /  $855 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADP-ribosylation factor-like protein 2-binding protein (ARL2BP), Recombinant Protein

 Also Known As   

Recombinant Human ADP-ribosylation factor-like protein 2-binding protein

 Product Synonym Names    Binder of ARF2 protein 1
 Product Gene Name   

ARL2BP recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-163aa; Full Length
 Sequence    MDALEGESFA LSFSSASDAE FDAVVGYLED IIMDDEFQLL QRNFMDKYYL EFEDTEENKL IYTPIFNEYI SLVEKYIEEQ LLQRIPEFNM AAFTTTLQHH KDEVAGDIFD MLLTFTDFLA FKEMFLDYRA EKEGRGLDLS SGLVVTSLCK SSSLPASQNN LRH
 OMIM    615407
 3D Structure    ModBase 3D Structure for Q9Y2Y0
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 Host    E Coli
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ARL2BP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ARL2BP recombinant protein

   Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
 Product Categories/Family for ARL2BP recombinant protein    Signal Transduction
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 SDS-PAGE of ARL2BP recombinant protein    ARL2BP recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for ARL2BP. It may not necessarily be applicable to this product.
 NCBI GI #    6912268
 NCBI GeneID    23568
 NCBI Accession #    NP_036238.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012106.3 [Other Products]
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 UniProt Primary Accession #    Q9Y2Y0 [Other Products]
 UniProt Secondary Accession #    Q504R0; B3KQJ5 [Other Products]
 UniProt Related Accession #    Q9Y2Y0 [Other Products]
 Molecular Weight    46.2kD
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 NCBI Official Full Name    ADP-ribosylation factor-like protein 2-binding protein
 NCBI Official Synonym Full Names    ADP ribosylation factor like GTPase 2 binding protein
 NCBI Official Symbol    ARL2BP [Similar Products]
 NCBI Official Synonym Symbols   
BART; RP66; BART1
[Similar Products]
 NCBI Protein Information    ADP-ribosylation factor-like protein 2-binding protein
 UniProt Protein Name    ADP-ribosylation factor-like protein 2-binding protein
 UniProt Synonym Protein Names   
Binder of ARF2 protein 1
 Protein Family    ADP-ribosylation factor-like protein 2-binding protein
 UniProt Gene Name    ARL2BP [Similar Products]
 UniProt Synonym Gene Names    BART; BART1; ARF-like 2-binding protein; ARL2-binding protein [Similar Products]
 UniProt Entry Name    AR2BP_HUMAN
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 NCBI Summary for ARL2BP    ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ARL2BP    ARL2BP: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. Belongs to the ARL2BP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.; Mitochondrial

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: centrosome; cilium; cytosol; midbody; mitochondrial intermembrane space; mitochondrial matrix; nucleus; spindle

Molecular Function: GTPase regulator activity; protein binding; transcription coactivator activity

Biological Process: energy reserve metabolic process; maintenance of protein localization in nucleus; positive regulation of tyrosine phosphorylation of Stat3 protein; regulation of catalytic activity; regulation of insulin secretion; signal transduction

Disease: Retinitis Pigmentosa With Or Without Situs Inversus
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Product References and Citations for ARL2BP recombinant protein

   The ARF-like 2 (ARL2) -binding protein, BART. Purification, cloning, and initial characterization.Sharer J.D., Kahn R.A.J. Biol. Chem. 274:27553-27561(1999) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.Nat. Genet. 36:40-45(2004)
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 Research Articles on ARL2BP    1. EBV also downregulates two immediate early genes by miR-BART20-5p.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ARL2BP recombinant proteinPathways associated with ARL2BP recombinant protein
 Reference Product  PubMed Publications
 ARL2 recombinant protein  >11 publications with ARL2BP and ARL2
 ARL3 recombinant protein  >4 publications with ARL2BP and ARL3
 Products by Pathway  Pathway Diagram
 Integration Of Energy Metabolism Pathway antibodies  Integration Of Energy Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Regulation Of Insulin Secretion Pathway antibodies  Regulation Of Insulin Secretion Pathway Diagram
Diseases associated with ARL2BP recombinant protein
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >4 publications with ARL2BP and Adenocarcinoma
 Neoplasm Metastasis Antibodies  >2 publications with ARL2BP and Neoplasm Metastasis
 Ovarian Diseases Antibodies  >1 publications with ARL2BP and Ovarian Diseases
 Liver Neoplasms Antibodies  >1 publications with ARL2BP and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with ARL2BP and Liver Diseases
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