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AIF1L recombinant protein

Scan QR to view Datasheet Catalog #    MBS203979
SDS-PAGE
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AIF1L, Recombinant Protein

 Also Known As   

AIF1L, 1-150aa, Human, His tag, E Coli

 Product Synonym Names    Allograft inflammatory factor 1-like isoform 1; C9orf58; FLJ12783; IBA2; MGC29466
 Product Gene Name   

AIF1L recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MSGELSNRFQ GGKAFGLLKA RQERRLAEIN REFLCDQKYS DEENLPEKLT AFKEKYMEFD LNNEGEIDLM SLKRMMEKLG VPKTHLEMKK MISEVTGGVS DTISYRDFVN MMLGKRSAVL KLVMMFEGKA NESSPKPVGP PPERDIASLP
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 Purity/Purification    > 95% by SDS - PAGE
 Form/Format    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl, 1mM DTT
 Concentration    1.0 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag    His-tag
 Expression System    E Coli
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of AIF1L recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for AIF1L recombinant protein

   AIF1L, also known as allograft inflammatory factor 1-like, is a cytoplasmic, cytokine-induced, calcium-binding protein first discovered in rat cardiac allografts with chronic rejection. This protein is a marker of human microglia and is expressed by macrophages in injured skeletal muscle and regulates reduced proliferation and differentiation of satellite cells. Recombinant human AIF1L protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
 Product Categories/Family for AIF1L recombinant protein    Cytoskeleton
 Applications Tested/Suitable for AIF1L recombinant protein   

SDS-PAGE

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 SDS-PAGE of AIF1L recombinant protein    AIF1L recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for AIF1L. It may not necessarily be applicable to this product.
 NCBI GI #    13899241
 NCBI GeneID    83543
 NCBI Accession #    NP_113614 [Other Products]
 NCBI GenBank Nucleotide #    NM_031426.3 [Other Products]
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 UniProt Secondary Accession #    Q6ZR40; Q8NAX7; Q8WU47; Q9H9G0; B2RBC4 [Other Products]
 UniProt Related Accession #    Q9BQI0 [Other Products]
 Molecular Weight    19.2 kDa (170aa), confirmed by MALDI-TOF
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 NCBI Official Full Name    allograft inflammatory factor 1-like isoform 1
 NCBI Official Synonym Full Names    allograft inflammatory factor 1-like
 NCBI Official Symbol    AIF1L [Similar Products]
 NCBI Official Synonym Symbols   
IBA2; C9orf58
[Similar Products]
 NCBI Protein Information    allograft inflammatory factor 1-like; ionized calcium binding adapter molecule 2; ionized calcium-binding adapter molecule 2
 UniProt Protein Name    Allograft inflammatory factor 1-like
 UniProt Synonym Protein Names   
Ionized calcium-binding adapter molecule 2
 Protein Family    Allograft inflammatory factor
 UniProt Gene Name    AIF1L [Similar Products]
 UniProt Synonym Gene Names    C9orf58; IBA2 [Similar Products]
 UniProt Entry Name    AIF1L_HUMAN
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 UniProt Comments for AIF1L    IBA2: Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for function. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 9q34.13-q34.3

Cellular Component: focal adhesion; cytoplasm; actin filament; actin cytoskeleton

Molecular Function: actin filament binding; calcium ion binding
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Product References and Citations for AIF1L recombinant protein

   utans u, et al. (1995). J. Clin. Invest., 95: 2954-2962
Deininger M.H., et al. (2000). Acta Neuropathol., 100: 673-680
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 Research Articles on AIF1L    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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