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Add To Compare List APOA1 recombinant protein Catalog # MBS5310711 Unit / Price 0.1 mL / $530 +1 FREE 8GB USB 5x0.1 mL / $2,195 +2 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name APOA1, Recombinant Protein Full Product Name APOA1 protein Product Synonym Names Recombinant Mouse APOA1 protein with His tag; Mouse APOA1 protein; Recombinant APOA1 protein; Apolipoprotein A-I protein; Alp-1 protein; apo-AI protein; Apoa-1 protein; apoA-I protein; Brp-14 protein; Ltw-1 protein; Lvtw-1 protein; Sep-1 protein; Sep-2 protein; Sep2 protein; Apolipoprotein AI protein Product Gene Name APOA1 recombinant protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 25-264 amino acids Sequence MGSSHHHHHH SSGLVPRGSH MGSDEPQSQW DKVKDFANVY VDAVKDSGRD YVSQFESSSL GQQLNLNLLE NWDTLGSTVS QLQERLGPLT RDFWDNLEKE TDWVRQEMNK DLEEVKQKVQ PYLDEFQKKW KEDVELYRQK VAPLGAELQE SARQKLQELQ GRLSPVAEEF RDRMRTHVDS LRTQLAPHSE QMRESLAQRL AELKSNPTLN EYHTRAKTHL KTLGEKARPA LEDLRHSLMP MLETLKTQVQ SVIDKASETL TAQ OMIM 105200 Host E Coli Specificity Human Purity/Purification > 90% pure Form/Format Liquid in PBS (pH 7.4) containing 20% glycerol and 1mM DTT Concentration 1 mg/ml (lot specific) Species Mouse Tag His tag Preparation and Storage Store at 4 degree C for short term. For long term storage, aliquot and store at-20 degree C.Avoid repeated freeze thaw cycles. Other Notes Small volumes of APOA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for APOA1 recombinant protein Apoa1 also known as Apolipoprotein A-I, is the major protein component of high density lipoprotein (HDL) in plasma. This protein promotes cholesterol efflux from tissues to the liver for excretion. And it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apoa1 are associated with HDL deficiency including Tangier disease. Recombinant mouse Apoa1, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques Product Categories/Family for APOA1 recombinant protein Cardiac Markers Applications Tested/Suitable for APOA1 recombinant protein SDS-PAGE, Control SDS-Page of APOA1 recombinant protein Figure annotation denotes ug of protein loaded and % gel used. TOP NCBI/Uniprot data below describe general gene information for APOA1. It may not necessarily be applicable to this product. NCBI GI # 823670702 NCBI GeneID 335 NCBI Accession # AKI70562.1 [Other Products] UniProt Secondary Accession # Q6LDN9; Q6Q785; Q9UCS8; Q9UCT8; A8K866[Other Products] UniProt Related Accession # P02647[Other Products] Molecular Weight 30.3 kDa TOP NCBI Official Full Name APOA1, partial NCBI Official Synonym Full Names apolipoprotein A1 NCBI Official Symbol APOA1 [Similar Products] NCBI Official Synonym Symbols apo(a) [Similar Products] NCBI Protein Information apolipoprotein A-I UniProt Protein Name Apolipoprotein A-I UniProt Synonym Protein Names Apolipoprotein A1 Protein Family Apolipoprotein UniProt Gene Name APOA1 [Similar Products] UniProt Synonym Gene Names Apo-AI; ApoA-I; ProapoA-I [Similar Products] TOP NCBI Summary for APOA1 This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015] TOP UniProt Comments for APOA1 Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. Research Articles on APOA1 1. Low-dose lipid-free apoA-I treatment in atherosclerotic mice preserves and restores collecting lymphatic vessels function by direct and indirect mechanisms. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with APOA1 recombinant protein Reference Product PubMed Publications APOB recombinant protein >674 publications with APOA1 and APOB APOE recombinant protein >204 publications with APOA1 and APOE ABCA1 recombinant protein >199 publications with APOA1 and ABCA1 APOC3 recombinant protein >92 publications with APOA1 and APOC3 CETP recombinant protein >75 publications with APOA1 and CETP APOA2 recombinant protein >56 publications with APOA1 and APOA2 LCAT recombinant protein >53 publications with APOA1 and LCAT LPL recombinant protein >51 publications with APOA1 and LPL ALB recombinant protein >12 publications with APOA1 and ALB MTTP recombinant protein >5 publications with APOA1 and MTTP Pathways associated with APOA1 recombinant protein Products by Pathway Pathway Diagram ABC Transporters In Lipid Homeostasis Pathway antibodies ABC Transporters In Lipid Homeostasis Pathway Diagram ABC-family Proteins Mediated Transport Pathway antibodies ABC-family Proteins Mediated Transport Pathway Diagram African Trypanosomiasis Pathway antibodies African Trypanosomiasis Pathway Diagram African Trypanosomiasis Pathway antibodies African Trypanosomiasis Pathway Diagram Amyloid Fiber Formation Pathway antibodies Amyloid Fiber Formation Pathway Diagram Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram Chylomicron-mediated Lipid Transport Pathway antibodies Chylomicron-mediated Lipid Transport Pathway Diagram Composition Of Lipid Particles Pathway antibodies Composition Of Lipid Particles Pathway Diagram FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram Fat Digestion And Absorption Pathway antibodies Fat Digestion And Absorption Pathway Diagram Diseases associated with APOA1 recombinant protein Disease Name Pubmed Publications Cardiovascular Diseases Antibodies >658 publications with APOA1 and Cardiovascular Diseases Atherosclerosis Antibodies >405 publications with APOA1 and Atherosclerosis Lipid Metabolism Disorders Antibodies >281 publications with APOA1 and Lipid Metabolism Disorders Dyslipidemias Antibodies >252 publications with APOA1 and Dyslipidemias Inflammation Antibodies >181 publications with APOA1 and Inflammation Hyperlipidemias Antibodies >158 publications with APOA1 and Hyperlipidemias Coronary Artery Disease Antibodies >152 publications with APOA1 and Coronary Artery Disease Hypertension Antibodies >113 publications with APOA1 and Hypertension Liver Diseases Antibodies >91 publications with APOA1 and Liver Diseases Hypercholesterolemia Antibodies >90 publications with APOA1 and Hypercholesterolemia Organs/Tissues associated with APOA1 recombinant protein Organ/Tissue Name Pubmed Publications Blood Antibodies >1167 publications with APOA1 and Blood Liver Antibodies >266 publications with APOA1 and Liver Heart Antibodies >239 publications with APOA1 and Heart Brain Antibodies >60 publications with APOA1 and Brain Muscle Antibodies >46 publications with APOA1 and Muscle Lung Antibodies >41 publications with APOA1 and Lung Intestine Antibodies >24 publications with APOA1 and Intestine Ovary Antibodies >22 publications with APOA1 and Ovary Pancreas Antibodies >10 publications with APOA1 and Pancreas Testis Antibodies >6 publications with APOA1 and Testis TOP © 2006-24 MyBioSource.com. 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