NP_415299.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
Molecular Weight
24,140 Da
NCBI Official Full Name
dethiobiotin synthetase
NCBI Protein Information
dethiobiotin synthetase
UniProt Protein Name
ATP-dependent dethiobiotin synthetase BioD 1
UniProt Synonym Protein Names
DTB synthetase 1; DTBS 1; Dethiobiotin synthase
UniProt Synonym Gene Names
NCBI Summary for bioD1
False positive lipoprotein prediction, verified amino terminus, Met is cleaved. [More information is available at EcoGene: EG10120]. Dethiobiotin synthetase catalyzes the first ring closure in the biosynthesis of biotin, which is the penultimate step in the biosynthesis pathway. [More information is available at EcoCyc: EG10120].
UniProt Comments for bioD1
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring. Only CTP can partially replace ATP while diaminobiotin is only 37% as effective as 7,8-diaminopelargonic acid.
Research Articles on bioD1
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Products associated with bioD1 recombinant protein
Pathways associated with bioD1 recombinant protein
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