NP_001289142.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
12,496 Da
NCBI Official Full Name
ATP synthase-coupling factor 6, mitochondrial
NCBI Official Synonym Full Names
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
NCBI Official Synonym Symbols
NCBI Protein Information
ATP synthase-coupling factor 6, mitochondrial
UniProt Protein Name
ATP synthase-coupling factor 6, mitochondrial
UniProt Synonym Gene Names
NCBI Summary for Atp5j
The protein encoded by this gene is a component of mitochondrial adenosine triphosphate synthase, which catalyzes the conversion of ATP from ADP. Mitochondrial adenosine triphosphate synthase consists of extrinsic and intrinsic membrane domains that are joined by a stalk. The protein encoded by this gene is a subunit of the stalk domain. A bi-directional promoter that drives expression of this gene has been has been identified. Pseudogenes of this gene are found on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
UniProt Comments for Atp5j
Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha3beta3 subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
Research Articles on Atp5j
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Products associated with Atp5j recombinant protein
Pathways associated with Atp5j recombinant protein
Diseases associated with Atp5j recombinant protein
Organs/Tissues associated with Atp5j recombinant protein
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