NP_001164509.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
45.9 kDa
NCBI Official Full Name
acetylserotonin O-methyltransferase isoform 1
NCBI Official Synonym Full Names
acetylserotonin O-methyltransferase
NCBI Protein Information
acetylserotonin O-methyltransferase
UniProt Protein Name
Acetylserotonin O-methyltransferase
UniProt Synonym Protein Names
Hydroxyindole O-methyltransferase; HIOMT
UniProt Synonym Gene Names
NCBI Summary for ASMT
This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010]
UniProt Comments for ASMT
Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity.
Research Articles on ASMT
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Products associated with ASMT recombinant protein
Pathways associated with ASMT recombinant protein
Diseases associated with ASMT recombinant protein
Organs/Tissues associated with ASMT recombinant protein
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