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ASAH1 recombinant protein :: Acid ceramidase (ASAH1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1320445 ASAH1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $785 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $900 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,030 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,050 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,160 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,205 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,275 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,305 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,365 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,650 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,875 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,935 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,075 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,495 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Acid ceramidase (ASAH1), Recombinant Protein

 Also Known As   

Recombinant Bovine Acid ceramidase (ASAH1)

 Product Synonym Names    Acid ceramidase; AC; ACDase; Acid CDase; EC=3.5.1.23; Acylsphingosine deacylase; N-acylsphingosine amidohydrolase
 Product Gene Name   

ASAH1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    21-395aa; full length protein
 Sequence    AQQVPPWTED CRKSTYPPSG PTYRGPVPWY TINLDLPPYK RWHELMVVKA PALKVIVNSM KNIVNAFVPS GKIIHLVDQK LPGLLGNFPG PFEEEMKGIA AVTEIPLGEI ILFNIFYEFF TICTSIITED KEGHLLHGRN LDFGVFLGWN INNDTWVITE ELKPLTVNLD FQRNNKTLFK ATTFAGYVGM LTGFKPGLFS VTLNERFSID GGFMGVMEWI LGKKDAQWVG FIIRSVLENS TSYEETKNIL TKTKILAPAY FILGGNQSGE GCVITRDRKQ SLDIYELDPK HGRWYVVQTN YDRWKNPFFL DDRRTPAKMC LNQTTQENIS FATIYDVLST KPILNKLTVY TVLIDVTKGQ FETYLRDCPD PCIGW
 3D Structure    ModBase 3D Structure for Q17QB3
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Bos taurus (Bovine)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ASAH1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for ASAH1 recombinant protein

   This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene.
NCBI/Uniprot data below describe general gene information for ASAH1. It may not necessarily be applicable to this product.
 NCBI GI #    186972122
 NCBI GeneID    510620
 NCBI Accession #    NP_001068927.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001075459.2 [Other Products]
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 UniProt Primary Accession #    Q17QB3 [Other Products]
 UniProt Related Accession #    Q17QB3 [Other Products]
 Molecular Weight    44,965 Da
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 NCBI Official Full Name    acid ceramidase
 NCBI Official Synonym Full Names    N-acylsphingosine amidohydrolase (acid ceramidase) 1<
 NCBI Official Symbol    ASAH1 [Similar Products]
 NCBI Protein Information    acid ceramidase; AC; ACDase; acid CDase; acylsphingosine deacylase
 UniProt Protein Name    Acid ceramidase
 UniProt Synonym Protein Names   
Acylsphingosine deacylase; N-acylsphingosine amidohydrolase
 Protein Family    Acid ceramidase
 UniProt Gene Name    ASAH1 [Similar Products]
 UniProt Synonym Gene Names    AC; ACDase; Acid CDase [Similar Products]
 UniProt Entry Name    ASAH1_BOVIN
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 UniProt Comments for ASAH1    Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ASAH1 recombinant proteinPathways associated with ASAH1 recombinant protein
 Reference Product  PubMed Publications
 SMPD1 recombinant protein  >61 publications with ASAH1 and SMPD1
 SPHK1 recombinant protein  >3 publications with ASAH1 and SPHK1
 GALC recombinant protein  >2 publications with ASAH1 and GALC
 UGCG recombinant protein  >1 publications with ASAH1 and UGCG
 SGPP1 recombinant protein  >1 publications with ASAH1 and SGPP1
 SPHK2 recombinant protein  >1 publications with ASAH1 and SPHK2
 Products by Pathway  Pathway Diagram
 Glycosphingolipid Metabolism Pathway antibodies  Glycosphingolipid Metabolism Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Signal Transduction Of S1P Pathway antibodies  Signal Transduction Of S1P Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
Diseases associated with ASAH1 recombinant proteinOrgans/Tissues associated with ASAH1 recombinant protein
 Disease Name  Pubmed Publications
 Lipidoses Antibodies  >28 publications with ASAH1 and Lipidoses
 Farber Lipogranulomatosis Antibodies  >27 publications with ASAH1 and Farber Lipogranulomatosis
 Necrosis Antibodies  >15 publications with ASAH1 and Necrosis
 Liver Diseases Antibodies  >11 publications with ASAH1 and Liver Diseases
 Fatty Liver Antibodies  >8 publications with ASAH1 and Fatty Liver
 Inflammation Antibodies  >7 publications with ASAH1 and Inflammation
 Fibrosis Antibodies  >6 publications with ASAH1 and Fibrosis
 Pain Antibodies  >4 publications with ASAH1 and Pain
 Drug-Induced Liver Injury Antibodies  >4 publications with ASAH1 and Drug-Induced Liver Injury
 Kidney Diseases Antibodies  >4 publications with ASAH1 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >17 publications with ASAH1 and Skin
 Liver Antibodies  >11 publications with ASAH1 and Liver
 Kidney Antibodies  >6 publications with ASAH1 and Kidney
 Brain Antibodies  >6 publications with ASAH1 and Brain
 Muscle Antibodies  >4 publications with ASAH1 and Muscle
 Pancreas Antibodies  >2 publications with ASAH1 and Pancreas
 Adipose Tissue Antibodies  >1 publications with ASAH1 and Adipose Tissue
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