NP_001029186.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
63,115 Da
NCBI Official Full Name
acid-sensing ion channel 2 isoform MDEG1
NCBI Official Synonym Full Names
acid sensing ion channel subunit 2
NCBI Official Synonym Symbols
MDEG; Accn1; BNC1k; BNaC1; MDEG1; MDEG2 [Similar Products]
NCBI Protein Information
acid-sensing ion channel 2
UniProt Protein Name
Acid-sensing ion channel 2
UniProt Synonym Protein Names
Amiloride-sensitive brain sodium channel; Amiloride-sensitive brain sodium channel 2; Amiloride-sensitive cation channel 1, neuronal; Amiloride-sensitive cation channel neuronal 1; Brain sodium channel 1; BNC1; BNaC1; Mammalian degenerin homolog
UniProt Synonym Gene Names
NCBI Summary for Asic2
member of the degenerin/epithelial Na(+) channel superfamily; permeable for Na(+), K(+) and Li(+); mutations may lead to a form of hereditary neurodegeneration; may be important for pain sensation [RGD, Feb 2006]
UniProt Comments for Asic2
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li+ and K+. Activation by an extracellular pH drop is followed by a rapid pH-independent inactivation. Heteromeric channel assembly seems to modulate channel properties.
Research Articles on Asic2
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Pathways associated with Asic2 recombinant protein
Diseases associated with Asic2 recombinant protein
Organs/Tissues associated with Asic2 recombinant protein
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