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ARPC2 recombinant protein :: Actin Related Protein 2/3 Complex Subunit 2 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2030074 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
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Unit / Price
0.01 mg  /  $145 +1 FREE 8GB USB
0.05 mg  /  $270 +1 FREE 8GB USB
0.1 mg  /  $425 +1 FREE 8GB USB
0.2 mg  /  $525 +1 FREE 8GB USB
0.5 mg  /  $1,010 +1 FREE 8GB USB
1 mg  /  $1,505 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Actin Related Protein 2/3 Complex Subunit 2 (ARPC2), Recombinant Protein

 Also Known As   

Recombinant Actin Related Protein 2/3 Complex Subunit 2 (ARPC2)

 Product Gene Name   

ARPC2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.
MILLEVNNR I IEETLALKFE NAAAGNKPEA VEVTFADFDG VLYHISNPNG DKTKVMVSIS LKFYKELQAH GADELLKRVY GSFLVNPESG YNVSLLYDLE NLPASKDSIV HQAGMLKRNC FASVFEKYFQ FQEEGKEGEN RAVIHYRDDE TMYVESKKDR VTVVFSTVFK DDDDVVIGKV FMQEFKEGRR ASHTAPQVLF SHREPPLELK DTDAAVGDNI GYITFVLFPR HTNASARDNT INLIHTFRDY LHYHIKCSKA YIHTRMRAKT SDFLKVLNRA RPDAEKKEMK TITGKTFSSR
 OMIM    604224
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 Host    Host: E Coli
Source: Prokaryotic expression
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 Purity/Purification    >90%
 Form/Format    Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
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 Predicted Molecular Mass    38.0kDa
 Accurate Molecular Mass (KD)    38kDa
 Endotoxin    <1.0EU per 1ug (determined by the LAL method)
 Expression System    Prokaryotic expression
 Tag    two N-terminal Tags, His-tag and S-tag
 Organism Species    Homo sapiens (Human)
 Fragment    Met1~Arg300
 Usage    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of ARPC2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for ARPC2 recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-Page of ARPC2 recombinant protein    ARPC2 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for ARPC2. It may not necessarily be applicable to this product.
 NCBI GI #    23238211
 NCBI GeneID    10109
 NCBI Accession #    NP_690601.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_152862.2 [Other Products]
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 UniProt Secondary Accession #    Q92801; Q9P1D4 [Other Products]
 UniProt Related Accession #    O15144 [Other Products]
 Molecular Weight    34,333 Da
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 NCBI Official Full Name    actin-related protein 2/3 complex subunit 2
 NCBI Official Synonym Full Names    actin related protein 2/3 complex, subunit 2, 34kDa
 NCBI Official Symbol    ARPC2 [Similar Products]
 NCBI Official Synonym Symbols   
ARC34; PRO2446; p34-Arc; PNAS-139
[Similar Products]
 NCBI Protein Information    actin-related protein 2/3 complex subunit 2
 UniProt Protein Name    Actin-related protein 2/3 complex subunit 2
 UniProt Synonym Protein Names   
Arp2/3 complex 34 kDa subunit; p34-ARC
 UniProt Gene Name    ARPC2 [Similar Products]
 UniProt Synonym Gene Names    ARC34; p34-ARC [Similar Products]
 UniProt Entry Name    ARPC2_HUMAN
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 NCBI Summary for ARPC2    This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ARPC2    ARPC2: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament. Belongs to the ARPC2 family.

Protein type: Cytoskeletal; Actin-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q36.1

Cellular Component: Golgi apparatus; neuron projection; Arp2/3 protein complex; focal adhesion; leading edge; cytoplasm; plasma membrane; synapse; cytosol; endosome; actin cytoskeleton

Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton; kinesin binding

Biological Process: axon guidance; ephrin receptor signaling pathway; innate immune response; cell motility
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 Research Articles on ARPC2    1. Recent reports now demonstrate a novel aspect of the ARP2/3 complex and the nucleating-promoting factors in the maintenance of endothelial barrier function and junction remodeling of established endothelial cell junctions.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ARPC2 recombinant proteinPathways associated with ARPC2 recombinant protein
 Reference Product  PubMed Publications
 ARPC4 recombinant protein  >12 publications with ARPC2 and ARPC4
 ARPC3 recombinant protein  >9 publications with ARPC2 and ARPC3
 ARPC5 recombinant protein  >7 publications with ARPC2 and ARPC5
 WASL recombinant protein  >1 publications with ARPC2 and WASL
 ARPC1B recombinant protein  >1 publications with ARPC2 and ARPC1B
 ACTR3 recombinant protein  >1 publications with ARPC2 and ACTR3
 ACTR2 recombinant protein  >1 publications with ARPC2 and ACTR2
 Products by Pathway  Pathway Diagram
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 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 CDC42 Signaling Events Pathway antibodies  CDC42 Signaling Events Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 EPHB-mediated Forward Signaling Pathway antibodies  EPHB-mediated Forward Signaling Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
Diseases associated with ARPC2 recombinant proteinOrgans/Tissues associated with ARPC2 recombinant protein
 Disease Name  Pubmed Publications
 Colitis, Ulcerative Antibodies  >2 publications with ARPC2 and Colitis, Ulcerative
 Hypertrophy Antibodies  >1 publications with ARPC2 and Hypertrophy
 Hypertension Antibodies  >1 publications with ARPC2 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >4 publications with ARPC2 and Muscle
 Blood Antibodies  >3 publications with ARPC2 and Blood
 Thymus Antibodies  >2 publications with ARPC2 and Thymus
 Connective Tissue Antibodies  >1 publications with ARPC2 and Connective Tissue
 Adipose Tissue Antibodies  >1 publications with ARPC2 and Adipose Tissue
 Lymph Node Antibodies  >1 publications with ARPC2 and Lymph Node
 Ovary Antibodies  >1 publications with ARPC2 and Ovary
 Liver Antibodies  >1 publications with ARPC2 and Liver
 Pancreas Antibodies  >1 publications with ARPC2 and Pancreas
 Kidney Antibodies  >1 publications with ARPC2 and Kidney
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