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Hrk recombinant protein :: Activator of apoptosis harakiri (Hrk) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS957520 Hrk recombinant protein
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Activator of apoptosis harakiri (Hrk), Recombinant Protein

 Also Known As   

Recombinant Mouse Activator of apoptosis harakiri (Hrk)

 Product Gene Name   

Hrk recombinant protein

[Similar Products]
 Product Synonym Gene Name    Recombinant Activator of apoptosis harakiri (Hrk); Activator of apoptosis harakiri; BH3-interacting domain-containing protein 3 Neuronal death protein DP5 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-92
 Chromosome Location    Chromosome: 5; NC_000071.6 (118169764..118189478). Location: 5 F; 5
 3D Structure    ModBase 3D Structure for P62816
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Hrk recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Hrk recombinant protein

   Hrk; Bid3, Dp5
NCBI/Uniprot data below describe general gene information for Hrk. It may not necessarily be applicable to this product.
 NCBI GI #    6671636
 NCBI GeneID    12123
 NCBI Accession #    NP_031571.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_007545.2 [Other Products]
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 UniProt Primary Accession #    P62816 [Other Products]
 UniProt Secondary Accession #    P70678 [Other Products]
 UniProt Related Accession #    P62816 [Other Products]
 Molecular Weight    10,078 Da [Similar Products]
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 NCBI Official Full Name    activator of apoptosis harakiri
 NCBI Official Synonym Full Names    harakiri, BCL2 interacting protein (contains only BH3 domain)
 NCBI Official Symbol    Hrk [Similar Products]
 NCBI Official Synonym Symbols   
DP5; Bid3; AI838259; harakiri
[Similar Products]
 NCBI Protein Information    activator of apoptosis harakiri; neuronal death protein DP5; BH3-interacting domain-containing protein 3; BH3 interacting (with BCL2 family) domain, apoptosis agonist
 UniProt Protein Name    Activator of apoptosis harakiri
 UniProt Synonym Protein Names   
BH3-interacting domain-containing protein 3; Neuronal death protein DP5
 Protein Family    Activator of apoptosis harakiri
 UniProt Gene Name    Hrk [Similar Products]
 UniProt Synonym Gene Names    Bid3; Dp5 [Similar Products]
 UniProt Entry Name    HRK_MOUSE
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 UniProt Comments for Hrk    HRK: Promotes apoptosis.

Protein type: Membrane protein, integral; Apoptosis

Cellular Component: membrane; mitochondrion; integral to membrane

Biological Process: regulation of apoptosis; cellular response to potassium ion starvation; apoptosis; positive regulation of neuron apoptosis
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 Research Articles on Hrk    1. Hrk deficiency does not significantly attenuate the widespread apoptosis seen in the Bcl-x (-/-) embryonic nervous system, indicating that other BH3-only molecules, alone or in combination, may regulate BAX activation in immature neurons.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Hrk recombinant proteinDiseases associated with Hrk recombinant protein
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >21 publications with Hrk and Neoplasms
 Nervous System Diseases Antibodies  >12 publications with Hrk and Nervous System Diseases
 Drug Toxicity Antibodies  >8 publications with Hrk and Drug Toxicity
 Skin Diseases Antibodies  >5 publications with Hrk and Skin Diseases
 Inflammation Antibodies  >4 publications with Hrk and Inflammation
 Necrosis Antibodies  >4 publications with Hrk and Necrosis
 Neurologic Manifestations Antibodies  >3 publications with Hrk and Neurologic Manifestations
 Brain Diseases Antibodies  >3 publications with Hrk and Brain Diseases
 Spinal Cord Diseases Antibodies  >2 publications with Hrk and Spinal Cord Diseases
 Vision Disorders Antibodies  >2 publications with Hrk and Vision Disorders
Organs/Tissues associated with Hrk recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with Hrk and Brain
 Spinal Cord Antibodies  >1 publications with Hrk and Spinal Cord
 Dorsal Root Ganglion Antibodies  >1 publications with Hrk and Dorsal Root Ganglion
 Embryonic Tissue Antibodies  >1 publications with Hrk and Embryonic Tissue
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