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Abr recombinant protein :: Active breakpoint cluster region-related protein (Abr) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1366544 Abr recombinant protein
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Active breakpoint cluster region-related protein (Abr), Recombinant Protein

 Also Known As   

Recombinant Mouse Active breakpoint cluster region-related protein (Abr) , partial

 Product Gene Name   

Abr recombinant protein

[Similar Products]
 Product Synonym Gene Name    Abr [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q5SSL4
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Abr recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Abr recombinant protein

   This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. This protein contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis, suggesting that Rho-related GTPases help coordinate motor skills and balance. Alternatively spliced transcript variants that encode different isoforms have been reported for this gene.
NCBI/Uniprot data below describe general gene information for Abr. It may not necessarily be applicable to this product.
 NCBI GI #    600971669
 NCBI GeneID    109934
 NCBI Accession #    NP_001278115.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001291186.1 [Other Products]
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 UniProt Primary Accession #    Q5SSL4 [Other Products]
 UniProt Secondary Accession #    Q3U5G0; Q3UQJ6; Q3UY38; Q5SYJ5; Q5SYJ7; Q5SYJ8; Q5SYJ9; Q6PCY1; Q6PDH3 [Other Products]
 UniProt Related Accession #    Q5SSL4 [Other Products]
 Molecular Weight    93,773 Da
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 NCBI Official Full Name    active breakpoint cluster region-related protein isoform 4
 NCBI Official Synonym Full Names    active BCR-related gene
 NCBI Official Symbol    Abr [Similar Products]
 NCBI Protein Information    active breakpoint cluster region-related protein
 UniProt Protein Name    Active breakpoint cluster region-related protein
 Protein Family    Active breakpoint cluster region-related protein
 UniProt Gene Name    Abr [Similar Products]
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 UniProt Comments for Abr    GTPase-activating protein for RAC and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them ().
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 Research Articles on Abr    1. Loss of abr expression causes defects in spine development.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Abr recombinant proteinDiseases associated with Abr recombinant protein
 Products by Pathway  Pathway Diagram
 Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies  Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
 G Alpha (12/13) Signalling Events Pathway antibodies  G Alpha (12/13) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 NRAGE Signals Death Through JNK Pathway antibodies  NRAGE Signals Death Through JNK Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Signaling By Rho GTPases Pathway antibodies  Signaling By Rho GTPases Pathway Diagram
 Signalling By NGF Pathway antibodies  Signalling By NGF Pathway Diagram
 Cyclic AMP Biosynthesis Pathway antibodies  Cyclic AMP Biosynthesis Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2008 publications with Abr and Nervous System Diseases
 Neoplasms Antibodies  >297 publications with Abr and Neoplasms
 Drug Toxicity Antibodies  >170 publications with Abr and Drug Toxicity
 Labyrinth Diseases Antibodies  >161 publications with Abr and Labyrinth Diseases
 Hearing Loss, Conductive Antibodies  >145 publications with Abr and Hearing Loss, Conductive
 Congenital Abnormalities Antibodies  >109 publications with Abr and Congenital Abnormalities
 Vascular Diseases Antibodies  >103 publications with Abr and Vascular Diseases
 Death Antibodies  >91 publications with Abr and Death
 Weight Loss Antibodies  >67 publications with Abr and Weight Loss
 Peripheral Nervous System Diseases Antibodies  >64 publications with Abr and Peripheral Nervous System Diseases
Organs/Tissues associated with Abr recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2666 publications with Abr and Brain
 Inner Ear Antibodies  >857 publications with Abr and Inner Ear
 Blood Antibodies  >297 publications with Abr and Blood
 Bone Antibodies  >177 publications with Abr and Bone
 Muscle Antibodies  >100 publications with Abr and Muscle
 Heart Antibodies  >69 publications with Abr and Heart
 Eye Antibodies  >68 publications with Abr and Eye
 Kidney Antibodies  >34 publications with Abr and Kidney
 Joint Antibodies  >29 publications with Abr and Joint
 Lung Antibodies  >22 publications with Abr and Lung
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