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TRAF3IP2 recombinant protein :: Adapter protein CIKS (TRAF3IP2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1109677 TRAF3IP2 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $995 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $1,060 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,185 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,340 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,435 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,435 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,480 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,505 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,625 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,105 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,150 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,160 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,470 +3 FREE 8GB USB
1 mg (Baculovirus)  /  $2,825 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Adapter protein CIKS (TRAF3IP2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Adapter protein CIKS (TRAF3IP2)

 Product Synonym Names    Adapter protein CIKS; Connection to IKK and SAPK/JNK; Nuclear factor NF-kappa-B activator 1; ACT1; TRAF3-interacting protein 2
 Product Gene Name   

TRAF3IP2 recombinant protein

[Similar Products]
 Product Synonym Gene Name    TRAF3IP2; C6orf2; C6orf4; C6orf5; C6orf6 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1109677 COA    COA PDF
 Sequence Positions    1-574. Full length.
 Sequence    MPPQLQETRM NRSIPVEVDE SEPYPSQLLK PIPEYSPEEE SEPPAPNIRN MAPNSLSAPT MLHNSSGDFS QAHSTLKLAN HQRPVSRQVT CLRTQVLEDS EDSFCRRHPG LGKAFPSGCS AVSEPASESV VGALPAEHQF SFMEKRNQWL VSQLSAASPD TGHDSDKSDQ SLPNASADSL GGSQEMVQRP QPHRNRAGLD LPTIDTGYDS QPQDVLGIRQ LERPLPLTSV CYPQDLPRPL RSREFPQFEP QRYPACAQML PPNLSPHAPW NYHYHCPGSP DHQVPYGHDY PRAAYQQVIQ PALPGQPLPG ASVRGLHPVQ KVILNYPSPW DHEERPAQRD CSFPGLPRHQ DQPHHQPPNR AGAPGESLEC PAELRPQVPQ PPSPAAVPRP PSNPPARGTL KTSNLPEELR KVFITYSMDT AMEVVKFVNF LLVNGFQTAI DIFEDRIRGI DIIKWMERYL RDKTVMIIVA ISPKYKQDVE GAESQLDEDE HGLHTKYIHR MMQIEFIKQG SMNFRFIPVL FPNAKKEHVP TWLQNTHVYS WPKNKKNILL RLLREEEYVA PPRGPLPTLQ VVPL
 OMIM    615527
 3D Structure    ModBase 3D Structure for O43734
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TRAF3IP2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for TRAF3IP2 recombinant protein

   TRAF3IP2; C6orf2, C6orf4, C6orf5, C6orf6
NCBI/Uniprot data below describe general gene information for TRAF3IP2. It may not necessarily be applicable to this product.
 NCBI GI #    256017209
 NCBI GeneID    10758
 NCBI Accession #    NP_001157753.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001164281.2 [Other Products]
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 UniProt Primary Accession #    O43734 [Other Products]
 UniProt Secondary Accession #    Q5R3A3; Q7Z6Q1; Q7Z6Q2; Q7Z6Q3; Q9H5W2; Q9H6Y3; Q9NS14; Q9UG72; B2RAY9; E1P555 [Other Products]
 UniProt Related Accession #    O43734 [Other Products]
 Molecular Weight    63,457 Da
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 NCBI Official Full Name    adapter protein CIKS isoform 3
 NCBI Official Synonym Full Names    TRAF3 interacting protein 2
 NCBI Official Symbol    TRAF3IP2 [Similar Products]
 NCBI Official Synonym Symbols   
ACT1; CIKS; C6orf2; C6orf4; C6orf5; C6orf6; CANDF8; PSORS13
[Similar Products]
 NCBI Protein Information    adapter protein CIKS; NFkB-activating protein ACT1; connection to IKK and SAPK/JNK; nuclear factor NF-kappa-B activator 1
 UniProt Protein Name    Adapter protein CIKS
 UniProt Synonym Protein Names   
Connection to IKK and SAPK/JNK; Nuclear factor NF-kappa-B activator 1; ACT1; TRAF3-interacting protein 2
 Protein Family    Adapter protein
 UniProt Gene Name    TRAF3IP2 [Similar Products]
 UniProt Synonym Gene Names    C6orf2; C6orf4; C6orf5; C6orf6; ACT1 [Similar Products]
 UniProt Entry Name    CIKS_HUMAN
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 NCBI Summary for TRAF3IP2    This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq, Aug 2009]
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 UniProt Comments for TRAF3IP2    TRAF3IP2: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK. Defects in TRAF3IP2 are the cause of susceptibility to psoriasis type 13 (PSORS13). PSORS13 is a common, chronic inflammatory disease of the skin with multifactorial etiology. It is characterized by red, scaly plaques usually found on the scalp, elbows and knees. These lesions are caused by abnormal keratinocyte proliferation and infiltration of inflammatory cells into the dermis and epidermis. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 6q21

Molecular Function: protein binding

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; immunoglobulin secretion; B cell apoptosis; humoral immune response

Disease: Candidiasis, Familial, 8; Psoriasis 13, Susceptibility To
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 Research Articles on TRAF3IP2    1. This study provides evidence that TRAF5 and TRAF3IP2 genes are involved in the development ofBehcet's disease (BD) and Vogt-Koyanagi-Harada (VKH) syndrome.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TRAF3IP2 recombinant proteinPathways associated with TRAF3IP2 recombinant protein
 Reference Product  PubMed Publications
 IL17A recombinant protein  >44 publications with TRAF3IP2 and IL17A
 TRAF6 recombinant protein  >18 publications with TRAF3IP2 and TRAF6
 IKBKB recombinant protein  >10 publications with TRAF3IP2 and IKBKB
 CD40 recombinant protein  >9 publications with TRAF3IP2 and CD40
 TRAF5 recombinant protein  >7 publications with TRAF3IP2 and TRAF5
 TRAF3 recombinant protein  >5 publications with TRAF3IP2 and TRAF3
 CHUK recombinant protein  >5 publications with TRAF3IP2 and CHUK
 IKBKG recombinant protein  >1 publications with TRAF3IP2 and IKBKG
 Products by Pathway  Pathway Diagram
 IL17 Signaling Pathway antibodies  IL17 Signaling Pathway Diagram
Diseases associated with TRAF3IP2 recombinant proteinOrgans/Tissues associated with TRAF3IP2 recombinant protein
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >50 publications with TRAF3IP2 and Necrosis
 Inflammation Antibodies  >34 publications with TRAF3IP2 and Inflammation
 Psoriasis Antibodies  >23 publications with TRAF3IP2 and Psoriasis
 Disease Models, Animal Antibodies  >13 publications with TRAF3IP2 and Disease Models, Animal
 Nervous System Diseases Antibodies  >10 publications with TRAF3IP2 and Nervous System Diseases
 Arthritis, Psoriatic Antibodies  >10 publications with TRAF3IP2 and Arthritis, Psoriatic
 Heart Diseases Antibodies  >5 publications with TRAF3IP2 and Heart Diseases
 Cardiovascular Diseases Antibodies  >5 publications with TRAF3IP2 and Cardiovascular Diseases
 Fibrosis Antibodies  >2 publications with TRAF3IP2 and Fibrosis
 Hypertrophy Antibodies  >2 publications with TRAF3IP2 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >29 publications with TRAF3IP2 and Blood
 Skin Antibodies  >13 publications with TRAF3IP2 and Skin
 Lung Antibodies  >7 publications with TRAF3IP2 and Lung
 Heart Antibodies  >6 publications with TRAF3IP2 and Heart
 Kidney Antibodies  >5 publications with TRAF3IP2 and Kidney
 Muscle Antibodies  >5 publications with TRAF3IP2 and Muscle
 Bone Antibodies  >4 publications with TRAF3IP2 and Bone
 Brain Antibodies  >3 publications with TRAF3IP2 and Brain
 Bone Marrow Antibodies  >2 publications with TRAF3IP2 and Bone Marrow
 Liver Antibodies  >2 publications with TRAF3IP2 and Liver
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