NP_001269154.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,668 Da
NCBI Official Full Name
adenosine deaminase 2 isoform a
NCBI Official Synonym Full Names
adenosine deaminase 2
NCBI Protein Information
adenosine deaminase 2; adenosine deaminase CECR1
UniProt Protein Name
Adenosine deaminase 2
UniProt Synonym Protein Names
Cat eye syndrome critical region protein 1
NCBI Summary for CECR1
This gene encodes a member of a subfamily of the adenosine deaminase protein family. The encoded protein is one of two adenosine deaminases found in humans, which regulate levels of the signaling molecule, adenosine. The encoded protein is secreted from monocytes undergoing differentiation and may regulate cell proliferation and differentiation. This gene may be responsible for some of the phenotypic features associated with cat eye syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Comments for CECR1
Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity.
Research Articles on CECR1
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Pathways associated with CECR1 recombinant protein
Diseases associated with CECR1 recombinant protein
Organs/Tissues associated with CECR1 recombinant protein
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