NP_000666.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
adenosine receptor A2a
NCBI Official Synonym Full Names
adenosine A2a receptor
NCBI Protein Information
adenosine receptor A2a; adenosine A2 receptor; adenosine receptor subtype A2a
UniProt Protein Name
Adenosine receptor A2a
UniProt Synonym Gene Names
UniProt Entry Name
AA2AR_HUMAN
NCBI Summary for ADORA2A
This gene encodes a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. The encoded protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine. [provided by RefSeq, Jul 2008]
UniProt Comments for ADORA2A
ADORA2A: one of several receptor subtypes for adenosine. A G-protein coupled receptor. Activation is mediated by G proteins which activate adenylyl cyclase. Abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.
Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 22q11.23
Cellular Component: membrane; integral to plasma membrane; plasma membrane
Molecular Function: identical protein binding; protein binding; enzyme binding; adenosine receptor activity, G-protein coupled
Biological Process: central nervous system development; nerve growth factor receptor signaling pathway; blood circulation; apoptosis; adenylate cyclase activation; phagocytosis; G-protein signaling, coupled to cAMP nucleotide second messenger; cell-cell signaling; sensory perception; cellular defense response; cAMP biosynthetic process; inflammatory response; blood coagulation; adenosine receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway
Research Articles on ADORA2A
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Products associated with ADORA2A recombinant protein
Pathways associated with ADORA2A recombinant protein
Diseases associated with ADORA2A recombinant protein
Organs/Tissues associated with ADORA2A recombinant protein
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