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Ak1 recombinant protein :: Adenylate kinase isoenzyme 1 (Ak1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1092314 Ak1 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $940 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $940 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,165 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,165 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,400 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,400 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,865 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,865 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Adenylate kinase isoenzyme 1 (Ak1), Recombinant Protein

 Also Known As   

Recombinant Rat Adenylate kinase isoenzyme 1 (Ak1)

 Product Synonym Names    Adenylate kinase isoenzyme 1; AK 1; EC=2.7.4.3; ATP-AMP transphosphorylase 1; Myokinase
 Product Gene Name   

Ak1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-194
 Sequence    MEDKLKKAKI IFVVGGPGSG KGTQCEKIVQ KYGYTHLSTG DLLRAEVSSG SSRGKMLSSI MEKGELVPLE TVLDMLRDAM LAKVDSSNGF LIDGYPREVK QGEEFERKIA QPTLLLYVDA GPETMTQRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV ISFYDKRGIV RKVNAEGSVD TVFSQVCTYL DSLK
 3D Structure    ModBase 3D Structure for P39069
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rattus norvegicus (Rat)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Ak1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Ak1. It may not necessarily be applicable to this product.
 NCBI GI #    61889092
 NCBI GeneID    24183
 NCBI Accession #    NP_077325.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_024349.3 [Other Products]
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 UniProt Primary Accession #    P39069 [Other Products]
 UniProt Secondary Accession #    Q5EBC5; Q9JJN3 [Other Products]
 UniProt Related Accession #    P39069 [Other Products]
 Molecular Weight    21,584 Da
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 NCBI Official Full Name    adenylate kinase isoenzyme 1
 NCBI Official Synonym Full Names    adenylate kinase 1
 NCBI Official Symbol    Ak1 [Similar Products]
 NCBI Official Synonym Symbols   
Ak 1
[Similar Products]
 NCBI Protein Information    adenylate kinase isoenzyme 1; myokinase; ATP:AMP phosphotransferase; ATP-AMP transphosphorylase 1; adenylate monophosphate kinase
 UniProt Protein Name    Adenylate kinase isoenzyme 1
 UniProt Synonym Protein Names   
ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; Adenylate monophosphate kinase; Myokinase
 Protein Family    Adenylate kinase
 UniProt Gene Name    Ak1 [Similar Products]
 UniProt Synonym Gene Names    AK 1 [Similar Products]
 UniProt Entry Name    KAD1_RAT
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 NCBI Summary for Ak1    catalyzes the conversion of ATP and AMP to ADP in adenine nucleotide metabolism [RGD, Feb 2006]
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 UniProt Comments for Ak1    AK1: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency (HAAKD). Belongs to the adenylate kinase family.

Protein type: Nucleotide Metabolism - purine; EC 2.7.4.6; Kinase, other; EC 2.7.4.3

Cellular Component: sarcomere; neuron projection; perinuclear region of cytoplasm; cytoplasm; plasma membrane; outer dense fiber

Molecular Function: nucleoside diphosphate kinase activity; adenylate kinase activity; ATP binding; phosphotransferase activity, phosphate group as acceptor

Biological Process: response to drug; positive regulation of neuron maturation; muscle development; olfactory bulb development; ADP biosynthetic process; nucleoside diphosphate phosphorylation; response to testosterone stimulus; AMP metabolic process; response to estradiol stimulus; neuron differentiation; ATP metabolic process; nucleoside triphosphate biosynthetic process; cerebellum development; inosine biosynthetic process; response to activity; cell cycle arrest; adenine metabolic process; nucleotide phosphorylation
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 Research Articles on Ak1    1. Data indicate that the beta-alanine administration was able to inhibit the enzyme pyruvate kinase, cytosolic creatine kinase, and adenylate kinase activities in cerebral cortex, and increase in cerebellum.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Ak1 recombinant proteinDiseases associated with Ak1 recombinant protein
 Products by Pathway  Pathway Diagram
 Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway antibodies  Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway Diagram
 Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway antibodies  Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >15 publications with Ak1 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >13 publications with Ak1 and Congenital Abnormalities
 Brain Diseases Antibodies  >10 publications with Ak1 and Brain Diseases
 Heart Diseases Antibodies  >8 publications with Ak1 and Heart Diseases
 Anemia Antibodies  >7 publications with Ak1 and Anemia
 Movement Disorders Antibodies  >5 publications with Ak1 and Movement Disorders
 Adenylate Kinase Deficiency, Hemolytic Anemia Due To Antibodies  >4 publications with Ak1 and Adenylate Kinase Deficiency, Hemolytic Anemia Due To
 Myocardial Ischemia Antibodies  >4 publications with Ak1 and Myocardial Ischemia
 Disease Models, Animal Antibodies  >3 publications with Ak1 and Disease Models, Animal
 Adenocarcinoma Antibodies  >2 publications with Ak1 and Adenocarcinoma
Organs/Tissues associated with Ak1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >46 publications with Ak1 and Muscle
 Brain Antibodies  >20 publications with Ak1 and Brain
 Heart Antibodies  >19 publications with Ak1 and Heart
 Embryonic Tissue Antibodies  >4 publications with Ak1 and Embryonic Tissue
 Eye Antibodies  >3 publications with Ak1 and Eye
 Pancreas Antibodies  >3 publications with Ak1 and Pancreas
 Connective Tissue Antibodies  >1 publications with Ak1 and Connective Tissue
 Adrenal Gland Antibodies  >1 publications with Ak1 and Adrenal Gland
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