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Ak1 recombinant protein :: Adenylate kinase isoenzyme 1 (Ak1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1092314 Ak1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $590 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $795 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $875 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $895 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,000 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,125 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,130 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,130 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,230 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,625 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,715 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,725 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,175 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Adenylate kinase isoenzyme 1 (Ak1), Recombinant Protein

 Also Known As   

Recombinant Rat Adenylate kinase isoenzyme 1 (Ak1)

 Product Gene Name   

Ak1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-194aa, full length protein
 Sequence    MEDKLKKAKI IFVVGGPGSG KGTQCEKIVQ KYGYTHLSTG DLLRAEVSSG SSRGKMLSSI MEKGELVPLE TVLDMLRDAM LAKVDSSNGF LIDGYPREVK QGEEFERKIA QPTLLLYVDA GPETMTQRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV ISFYDKRGIV RKVNAEGSVD TVFSQVCTYL DSLK
 3D Structure    ModBase 3D Structure for P39069
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Ak1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Ak1 recombinant protein

   Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
NCBI/Uniprot data below describe general gene information for Ak1. It may not necessarily be applicable to this product.
 NCBI GI #    61889092
 NCBI GeneID    24183
 NCBI Accession #    NP_077325.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_024349.3 [Other Products]
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 UniProt Primary Accession #    P39069 [Other Products]
 UniProt Secondary Accession #    Q5EBC5; Q9JJN3 [Other Products]
 UniProt Related Accession #    P39069 [Other Products]
 Molecular Weight    21,584 Da
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 NCBI Official Full Name    adenylate kinase isoenzyme 1
 NCBI Official Synonym Full Names    adenylate kinase 1
 NCBI Official Symbol    Ak1 [Similar Products]
 NCBI Official Synonym Symbols   
Ak 1
[Similar Products]
 NCBI Protein Information    adenylate kinase isoenzyme 1
 UniProt Protein Name    Adenylate kinase isoenzyme 1
 UniProt Synonym Protein Names   
ATP-AMP transphosphorylase 1
 Protein Family    Adenylate kinase
 UniProt Gene Name    Ak1 [Similar Products]
 UniProt Synonym Gene Names    AK 1 [Similar Products]
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 NCBI Summary for Ak1    catalyzes the conversion of ATP and AMP to ADP in adenine nucleotide metabolism [RGD, Feb 2006]
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 UniProt Comments for Ak1    Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
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 Research Articles on Ak1    1. Data indicate that the beta-alanine administration was able to inhibit the enzyme pyruvate kinase, cytosolic creatine kinase, and adenylate kinase activities in cerebral cortex, and increase in cerebellum.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Ak1 recombinant proteinDiseases associated with Ak1 recombinant protein
 Products by Pathway  Pathway Diagram
 Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway antibodies  Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway Diagram
 Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway antibodies  Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >15 publications with Ak1 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >13 publications with Ak1 and Congenital Abnormalities
 Brain Diseases Antibodies  >10 publications with Ak1 and Brain Diseases
 Heart Diseases Antibodies  >8 publications with Ak1 and Heart Diseases
 Anemia Antibodies  >7 publications with Ak1 and Anemia
 Movement Disorders Antibodies  >5 publications with Ak1 and Movement Disorders
 Adenylate Kinase Deficiency, Hemolytic Anemia Due To Antibodies  >4 publications with Ak1 and Adenylate Kinase Deficiency, Hemolytic Anemia Due To
 Myocardial Ischemia Antibodies  >4 publications with Ak1 and Myocardial Ischemia
 Disease Models, Animal Antibodies  >3 publications with Ak1 and Disease Models, Animal
 Adenocarcinoma Antibodies  >2 publications with Ak1 and Adenocarcinoma
Organs/Tissues associated with Ak1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >46 publications with Ak1 and Muscle
 Brain Antibodies  >20 publications with Ak1 and Brain
 Heart Antibodies  >19 publications with Ak1 and Heart
 Embryonic Tissue Antibodies  >4 publications with Ak1 and Embryonic Tissue
 Eye Antibodies  >3 publications with Ak1 and Eye
 Pancreas Antibodies  >3 publications with Ak1 and Pancreas
 Connective Tissue Antibodies  >1 publications with Ak1 and Connective Tissue
 Adrenal Gland Antibodies  >1 publications with Ak1 and Adrenal Gland
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