NP_001013075.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
36,135 Da
NCBI Official Full Name
aldo-keto reductase family 1 member C21
NCBI Official Synonym Full Names
aldo-keto reductase family 1, member C2
NCBI Official Synonym Symbols
NCBI Protein Information
aldo-keto reductase family 1 member C21
UniProt Protein Name
Aldo-keto reductase family 1 member C21
UniProt Synonym Protein Names
17-alpha-hydroxysteroid dehydrogenase; 17-alpha-HSD; 3(or 17)-alpha-hydroxysteroid dehydrogenase (EC:1.1.1.209); 3-alpha-hydroxysteroid dehydrogenase
UniProt Synonym Gene Names
UniProt Comments for Akr1c21
NADP-dependent 17-alpha-hydroxysteroid dehydrogenase that converts 5-alpha-androstane-3,17-dione into androsterone. Has lower 3-alpha-hydroxysteroid dehydrogenase activity. Has broad substrate specificity and acts on various 17-alpha-hydroxysteroids, 17-ketosteroids, 3-alpha hydroxysteroids and 3-ketosteroids. Reduction of keto groups is strictly stereoselective. Reduction of 17-ketosteroids yields only 17-alpha-hydroxysteroids. Likewise, reduction of 3-ketosteroids yields only 3-alpha-hydroxysteroids ().
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Products associated with Akr1c21 recombinant protein
Pathways associated with Akr1c21 recombinant protein
Diseases associated with Akr1c21 recombinant protein
Organs/Tissues associated with Akr1c21 recombinant protein
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