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ADRA2A recombinant protein :: Alpha-2A adrenergic receptor (ADRA2A) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS7007299 ADRA2A recombinant protein
Unit / Price
0.01 mg  /  $1,090 +1 FREE 8GB USB
0.05 mg  /  $1,595 +1 FREE 8GB USB
0.1 mg  /  $2,505 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Alpha-2A adrenergic receptor (ADRA2A), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Alpha-2A adrenergic receptor (ADRA2A)

 Product Gene Name   

ADRA2A recombinant protein

[Similar Products]
 Product Synonym Gene Name    ADRA2R; ADRAR [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-450aa; Full length protein
 Sequence    MGSLQPDAGN ASWNGTEAPG GGARATPYSL QVTLTLVCLA GLLMLLTVFG NVLVIIAVFT SRALKAPQNL FLVSLASADI LVATLVIPFS LANEVMGYWY FGKAWCEIYL ALDVLFCTSS IVHLCAISLD RYWSITQAIE YNLKRTPRRI KAIIITVWVI SAVISFPPLI SIEKKGGGGG PQPAEPRCEI NDQKWYVISS CIGSFFAPCL IMILVYVRIY QIAKRRTRVP PSRRGPDAVA APPGGTERRP NGLGPERSAG PGGAEAEPLP TQLNGAPGEP APAGPRDTDA LDLEESSSSD HAERPPGPRR PERGPRGKGK ARASQVKPGD SLPRRGPGAT GIGTPAAGPG EERVGAAKAS RWRGRQNREK RFTFVLAVVI GVFVVCWFPF FFTYTLTAVG CSVPRTLFKF FFWFGYCNSS LNPVIYTIFN HDFRRAFKKI LCRGDRKRIV
 OMIM    104210
 3D Structure    ModBase 3D Structure for P08913
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 Host    Cell Free Expression
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 Form/Format    Liquid containing glycerol
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol.
 Tag Information    Tag type will be determined during the manufacturing process.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ADRA2A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for ADRA2A recombinant protein    Transmembrane Protein
 Application Notes for ADRA2A recombinant protein    This is a recombinant transmembrane protein expressed in a cell-free expression system.
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NCBI/Uniprot data below describe general gene information for ADRA2A. It may not necessarily be applicable to this product.
 NCBI GI #    194353970
 NCBI GeneID    150
 NCBI Accession #    NP_000672.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_000681.3 [Other Products]
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 UniProt Primary Accession #    P08913 [Other Products]
 UniProt Secondary Accession #    Q2I8G2; Q2XN99; Q86TH8; Q9BZK1; B0LPF6 [Other Products]
 UniProt Related Accession #    P08913 [Other Products]
 Molecular Weight    48,957 Da
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 NCBI Official Full Name    alpha-2A adrenergic receptor
 NCBI Official Synonym Full Names    adrenoceptor alpha 2A
 NCBI Official Symbol    ADRA2A [Similar Products]
 NCBI Official Synonym Symbols   
ADRA2; ADRAR; ZNF32; ADRA2R; ALPHA2AAR
[Similar Products]
 NCBI Protein Information    alpha-2A adrenergic receptor
 UniProt Protein Name    Alpha-2A adrenergic receptor
 UniProt Synonym Protein Names   
Alpha-2 adrenergic receptor subtype C10; Alpha-2A adrenoreceptor; Alpha-2A adrenoceptor; Alpha-2AAR
 Protein Family    Alpha-2A adrenergic receptor
 UniProt Gene Name    ADRA2A [Similar Products]
 UniProt Synonym Gene Names    ADRA2R; ADRAR; Alpha-2A adrenoceptor; Alpha-2AAR [Similar Products]
 UniProt Entry Name    ADA2A_HUMAN
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 NCBI Summary for ADRA2A    Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADRA2A    Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.
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 Research Articles on ADRA2A    1. Study is in line with previous reports of an association between ADRA2A gene variants and general reaction time variability during response selection tasks
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ADRA2A recombinant proteinPathways associated with ADRA2A recombinant protein
 Reference Product  PubMed Publications
 ADRA2C recombinant protein  >185 publications with ADRA2A and ADRA2C
 P2RY12 recombinant protein  >9 publications with ADRA2A and P2RY12
 ADCY5 recombinant protein  >8 publications with ADRA2A and ADCY5
 CNR1 recombinant protein  >5 publications with ADRA2A and CNR1
 MTNR1B recombinant protein  >4 publications with ADRA2A and MTNR1B
 GNAZ recombinant protein  >2 publications with ADRA2A and GNAZ
 GNAI1 recombinant protein  >2 publications with ADRA2A and GNAI1
 AGT recombinant protein  >1 publications with ADRA2A and AGT
 Products by Pathway  Pathway Diagram
 Adrenaline Signalling Through Alpha-2 Adrenergic Receptor Pathway antibodies  Adrenaline Signalling Through Alpha-2 Adrenergic Receptor Pathway Diagram
 Adrenaline,noradrenaline Inhibits Insulin Secretion Pathway antibodies  Adrenaline,noradrenaline Inhibits Insulin Secretion Pathway Diagram
 Adrenoceptors Pathway antibodies  Adrenoceptors Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 G Alpha (z) Signalling Events Pathway antibodies  G Alpha (z) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
Diseases associated with ADRA2A recombinant proteinOrgans/Tissues associated with ADRA2A recombinant protein
 Disease Name  Pubmed Publications
 Hypertension Antibodies  >667 publications with ADRA2A and Hypertension
 Mental Disorders Antibodies  >619 publications with ADRA2A and Mental Disorders
 Pain Antibodies  >561 publications with ADRA2A and Pain
 Disease Models, Animal Antibodies  >313 publications with ADRA2A and Disease Models, Animal
 Heart Diseases Antibodies  >280 publications with ADRA2A and Heart Diseases
 Hypotension Antibodies  >232 publications with ADRA2A and Hypotension
 Depressive Disorder Antibodies  >172 publications with ADRA2A and Depressive Disorder
 Bradycardia Antibodies  >144 publications with ADRA2A and Bradycardia
 Tachycardia Antibodies  >140 publications with ADRA2A and Tachycardia
 Inflammation Antibodies  >116 publications with ADRA2A and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3353 publications with ADRA2A and Brain
 Heart Antibodies  >1239 publications with ADRA2A and Heart
 Nerve Antibodies  >1134 publications with ADRA2A and Nerve
 Kidney Antibodies  >581 publications with ADRA2A and Kidney
 Intestine Antibodies  >279 publications with ADRA2A and Intestine
 Eye Antibodies  >255 publications with ADRA2A and Eye
 Connective Tissue Antibodies  >226 publications with ADRA2A and Connective Tissue
 Pancreas Antibodies  >138 publications with ADRA2A and Pancreas
 Adrenal Gland Antibodies  >124 publications with ADRA2A and Adrenal Gland
 Stomach Antibodies  >124 publications with ADRA2A and Stomach
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