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NAPA recombinant protein :: Alpha-soluble NSF attachment protein (NAPA) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS965589 NAPA recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $700 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $945 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $975 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,030 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,115 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,215 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,225 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,260 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,465 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,765 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,840 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,915 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,355 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Alpha-soluble NSF attachment protein (NAPA), Recombinant Protein

 Also Known As   

Recombinant Human Alpha-soluble NSF attachment protein (NAPA)

 Product Gene Name   

NAPA recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-295aa, Full length protein
 Sequence    MDNSGKEAEA MALLAEAERK VKNSQSFFSG LFGGSSKIEE ACEIYARAAN MFKMAKNWSA AGNAFCQAAQ LHLQLQSKHD AATCFVDAGN AFKKADPQEA INCLMRAIEI YTDMGRFTIA AKHHISIAEI YETELVDIEK AIAHYEQSAD YYKGEESNSS ANKCLLKVAG YAALLEQYQK AIDIYEQVGT NAMDSPLLKY SAKDYFFKAA LCHFCIDMLN AKLAVQKYEE LFPAFSDSRE CKLMKKLLEA HEEQNVDSYT ESVKEYDSIS RLDQWLTTML LRIKKTIQGD EEDLR
 OMIM    603215
 3D Structure    ModBase 3D Structure for P54920
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of NAPA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for NAPA recombinant protein

   The SNARE hypothesis is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively. Platelets contain some of the same proteins, including NSF, p115
TAP, alpha-SNAP, gamma-SNAP, and the t-SNAREs syntaxin-2 and syntaxin-4, that are used in many vesicular transport processes in other cell types. Platelet exocytosis uses a molecular mechanism similar to that used by other secretory cells, such as neurons, although the proteins used by the platelet and their modes of regulation may be quite different.
NCBI/Uniprot data below describe general gene information for NAPA. It may not necessarily be applicable to this product.
 NCBI GI #    47933379
 NCBI GeneID    8775
 NCBI Accession #    NP_003818.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003827.3 [Other Products]
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 UniProt Primary Accession #    P54920 [Other Products]
 UniProt Secondary Accession #    Q96IK3; Q9BVJ3; A8K879 [Other Products]
 UniProt Related Accession #    P54920 [Other Products]
 Molecular Weight    33,233 Da
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 NCBI Official Full Name    alpha-soluble NSF attachment protein
 NCBI Official Synonym Full Names    NSF attachment protein alpha
 NCBI Official Symbol    NAPA [Similar Products]
 NCBI Official Synonym Symbols   
SNAPA
[Similar Products]
 NCBI Protein Information    alpha-soluble NSF attachment protein
 UniProt Protein Name    Alpha-soluble NSF attachment protein
 UniProt Synonym Protein Names   
N-ethylmaleimide-sensitive factor attachment protein alpha
 Protein Family    Na(+)/H(+) antiporter
 UniProt Gene Name    NAPA [Similar Products]
 UniProt Synonym Gene Names    SNAPA; SNAP-alpha [Similar Products]
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 NCBI Summary for NAPA    This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]
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 UniProt Comments for NAPA    Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane (PubMed:15980433).
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 Research Articles on NAPA    1. alphaSNAP is mainly expressed in the neuron brain tissue of patients with temporal lobe epilepsy. Its blood levels were significantly lower in these patients. alphaSNAP levels may increase epilepsy susceptibility.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NAPA recombinant proteinPathways associated with NAPA recombinant protein
 Reference Product  PubMed Publications
 NSF recombinant protein  >2 publications with NAPA and NSF
 STX1A recombinant protein  >1 publications with NAPA and STX1A
 Products by Pathway  Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Synaptic Vesicle Pathway antibodies  Synaptic Vesicle Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram
 Trans-Golgi Network Vesicle Budding Pathway antibodies  Trans-Golgi Network Vesicle Budding Pathway Diagram
Diseases associated with NAPA recombinant proteinOrgans/Tissues associated with NAPA recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >63 publications with NAPA and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >49 publications with NAPA and Nervous System Diseases
 Poisoning Antibodies  >20 publications with NAPA and Poisoning
 Kidney Diseases Antibodies  >18 publications with NAPA and Kidney Diseases
 Breast Neoplasms Antibodies  >14 publications with NAPA and Breast Neoplasms
 Inflammation Antibodies  >12 publications with NAPA and Inflammation
 Neurobehavioral Manifestations Antibodies  >9 publications with NAPA and Neurobehavioral Manifestations
 Disease Models, Animal Antibodies  >8 publications with NAPA and Disease Models, Animal
 Liver Diseases Antibodies  >7 publications with NAPA and Liver Diseases
 Cognition Disorders Antibodies  >7 publications with NAPA and Cognition Disorders
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >142 publications with NAPA and Blood
 Heart Antibodies  >63 publications with NAPA and Heart
 Kidney Antibodies  >44 publications with NAPA and Kidney
 Brain Antibodies  >35 publications with NAPA and Brain
 Liver Antibodies  >26 publications with NAPA and Liver
 Muscle Antibodies  >21 publications with NAPA and Muscle
 Vascular Antibodies  >14 publications with NAPA and Vascular
 Nerve Antibodies  >11 publications with NAPA and Nerve
 Skin Antibodies  >10 publications with NAPA and Skin
 Bone Antibodies  >9 publications with NAPA and Bone
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