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Add To Compare List Snca recombinant protein :: Alpha-synuclein (Snca) Recombinant Protein Catalog # MBS1181963 Unit / Price 0.02 mg (E-Coli) / $510 +1 FREE 8GB USB 0.1 mg (E-Coli) / $760 +1 FREE 8GB USB 0.02 mg (Yeast) / $820 +1 FREE 8GB USB 0.1 mg (Yeast) / $960 +1 FREE 8GB USB 0.02 mg (Baculovirus) / $1,070 +1 FREE 8GB USB 0.02 mg (Mammalian-Cell) / $1,305 +1 FREE 8GB USB 0.1 mg (Baculovirus) / $1,480 +1 FREE 8GB USB 1 mg (Yeast) / $1,875 +2 FREE 8GB USB 1 mg (E-Coli) / $2,060 +2 FREE 8GB USB 0.1 mg (Mammalian-Cell) / $2,110 +2 FREE 8GB USB 1 mg (Baculovirus) / $2,925 +3 FREE 8GB USB 0.5 mg (Mammalian-Cell) / $5,750 +7 FREE 8GB USB 5x1 mg (E-Coli) / $9,045 +10 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Alpha-synuclein (Snca), Recombinant Protein Full Product Name Recombinant Mouse Alpha-synuclein (Snca) Product Gene Name Snca recombinant protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 1-140aa, Full length protein Sequence MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP GSEAYEMPSE EGYQDYEPEA 3D Structure ModBase 3D Structure for O55042 Host E Coli or Yeast or Baculovirus or Mammalian Cell Purity/Purification Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific) Form/Format Lyophilized or liquid (Format to be determined during the manufacturing process) Tag Information This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information. Sterility Sterile filter available upon request. Endotoxin Low endotoxin available upon request. Species Mouse Preparation and Storage Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of Snca recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for Snca recombinant protein Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer s disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. NCBI/Uniprot data below describe general gene information for Snca. It may not necessarily be applicable to this product. NCBI GI # 109638747 NCBI GeneID 20617 NCBI Accession # NP_001035916.1 [Other Products] NCBI GenBank Nucleotide # NM_001042451.2 [Other Products] UniProt Primary Accession # O55042 [Other Products] UniProt Secondary Accession # Q3U130; Q9CXF8; Q9EQC3; Q9QUR3[Other Products] UniProt Related Accession # O55042[Other Products] Molecular Weight 14.5 kDa TOP NCBI Official Full Name alpha-synuclein NCBI Official Synonym Full Names synuclein, alpha NCBI Official Symbol Snca [Similar Products] NCBI Official Synonym Symbols NACP; alphaSYN; alpha-Syn [Similar Products] NCBI Protein Information alpha-synuclein UniProt Protein Name Alpha-synuclein UniProt Synonym Protein Names Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP Protein Family Alpha-synuclein UniProt Gene Name Snca [Similar Products] UniProt Synonym Gene Names Syn; NACP [Similar Products] TOP TOP UniProt Comments for Snca May be involved in the regulation of dopamine release and transport. Research Articles on Snca 1. Study shows that the age-dependent alpha-syn accumulation is correlated with an elevation of TRPC3 in the mitochondrial fractions isolated from monkey and mouse brains. In animal and cell models, alpha-syn overexpression was accompanied by an elevation of alpha-syn and TRPC3 in the mitochondrial fractions, and alpha-syn downregulation was associated with a reduction of the mitochondrial alpha-syn and TRPC3. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with Snca recombinant protein Reference Product PubMed Publications SNCB recombinant protein >73 publications with Snca and SNCB MAPT recombinant protein >50 publications with Snca and MAPT SNCAIP recombinant protein >30 publications with Snca and SNCAIP PARK2 recombinant protein >19 publications with Snca and PARK2 APP recombinant protein >16 publications with Snca and APP SLC6A3 recombinant protein >12 publications with Snca and SLC6A3 MAPK1 recombinant protein >5 publications with Snca and MAPK1 TOR1A recombinant protein >4 publications with Snca and TOR1A BAD recombinant protein >3 publications with Snca and BAD SQSTM1 recombinant protein >3 publications with Snca and SQSTM1 Pathways associated with Snca recombinant protein Products by Pathway Pathway Diagram Alzheimer's Disease Pathway antibodies Alzheimer's Disease Pathway Diagram Alzheimer's Disease Pathway antibodies Alzheimer's Disease Pathway Diagram Amyloids Pathway antibodies Amyloids Pathway Diagram Disease Pathway antibodies Disease Pathway Diagram EGFR1 Signaling Pathway antibodies EGFR1 Signaling Pathway Diagram Parkinson's Disease Pathway antibodies Parkinson's Disease Pathway Diagram Diseases associated with Snca recombinant protein Disease Name Pubmed Publications Nervous System Diseases Antibodies >1054 publications with Snca and Nervous System Diseases Brain Diseases Antibodies >1034 publications with Snca and Brain Diseases Neurodegenerative Diseases Antibodies >1021 publications with Snca and Neurodegenerative Diseases Movement Disorders Antibodies >901 publications with Snca and Movement Disorders Parkinsonian Disorders Antibodies >833 publications with Snca and Parkinsonian Disorders Parkinson Disease Antibodies >766 publications with Snca and Parkinson Disease Lewy Body Disease Antibodies >271 publications with Snca and Lewy Body Disease Nerve Degeneration Antibodies >162 publications with Snca and Nerve Degeneration Disease Models, Animal Antibodies >127 publications with Snca and Disease Models, Animal Drug Toxicity Antibodies >71 publications with Snca and Drug Toxicity Organs/Tissues associated with Snca recombinant protein Organ/Tissue Name Pubmed Publications Brain Antibodies >723 publications with Snca and Brain Embryonic Tissue Antibodies >28 publications with Snca and Embryonic Tissue Eye Antibodies >9 publications with Snca and Eye Liver Antibodies >6 publications with Snca and Liver Bone Antibodies >6 publications with Snca and Bone Sympathetic Ganglion Antibodies >6 publications with Snca and Sympathetic Ganglion Skin Antibodies >6 publications with Snca and Skin Lung Antibodies >4 publications with Snca and Lung Olfactory Mucosa Antibodies >2 publications with Snca and Olfactory Mucosa Prostate Antibodies >1 publications with Snca and Prostate TOP © 2006-24 MyBioSource.com. 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