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ABP1 recombinant protein :: Amiloride-sensitive amine oxidase [copper-containing] (ABP1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS966685 ABP1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $1,165 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $1,195 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,310 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,560 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,570 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,620 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,660 +2 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,735 +2 FREE 8GB USB
0.5 mg (Yeast)  /  $1,830 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,345 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,370 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,470 +3 FREE 8GB USB
1 mg (Yeast)  /  $2,770 +3 FREE 8GB USB
1 mg (Baculovirus)  /  $3,100 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Amiloride-sensitive amine oxidase [copper-containing] (ABP1), Recombinant Protein

 Also Known As   

Recombinant Human Amiloride-sensitive amine oxidase [copper-containing] (ABP1)

 Product Synonym Names    Amiloride-sensitive amine oxidase [copper-containing]; DAO; Diamine oxidase; EC=1.4.3.22; Amiloride-binding protein; ABP; Histaminase; Kidney amine oxidase; KAO
 Product Gene Name   

ABP1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    ABP1; AOC1; DAO1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    20-751aa; Full length protein
 Sequence    E PSPGTLPRKA GVFSDLSNQE LKAVHSFLWS KKELRLQPSS TTTMAKNTVF LIEMLLPKKY HVLRFLDKGE RHPVREARAV IFFGDQEHPN VTEFAVGPLP GPCYMRALSP RPGYQSSWAS RPISTAEYAL LYHTLQEATK PLHQFFLNTT GFSFQDCHDR CLAFTDVAPR GVASGQRRSW LIIQRYVEGY FLHPTGLELL VDHGSTDAGH WAVEQVWYNG KFYGSPEELA RKYADGEVDV VVLEDPLPGG KGHDSTEEPP LFSSHKPRGD FPSPIHVSGP RLVQPHGPRF RLEGNAVLYG GWSFAFRLRS SSGLQVLNVH FGGERIAYEV SVQEAVALYG GHTPAGMQTK YLDVGWGLGS VTHELAPGID CPETATFLDT FHYYDADDPV HYPRALCLFE MPTGVPLRRH FNSNFKGGFN FYAGLKGQVL VLRTTSTVYN YDYIWDFIFY PNGVMEAKMH ATGYVHATFY TPEGLRHGTR LHTHLIGNIH THLVHYRVDL DVAGTKNSFQ TLQMKLENIT NPWSPRHRVV QPTLEQTQYS WERQAAFRFK RKLPKYLLFT SPQENPWGHK RTYRLQIHSM ADQVLPPGWQ EEQAITWARY PLAVTKYRES ELCSSSIYHQ NDPWHPPVVF EQFLHNNENI ENEDLVAWVT VGFLHIPHSE DIPNTATPGN SVGFLLRPFN FFPEDPSLAS RDTVIVWPRD NGPNYVQRWI PEDRDCSMPP PFSYNGTYRP V
 OMIM    104610
 3D Structure    ModBase 3D Structure for P19801
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ABP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for ABP1 recombinant protein

   This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.
NCBI/Uniprot data below describe general gene information for ABP1. It may not necessarily be applicable to this product.
 NCBI GI #    73486661
 NCBI GeneID    26
 NCBI Accession #    NP_001082.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001091.3 [Other Products]
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 UniProt Primary Accession #    P19801 [Other Products]
 UniProt Secondary Accession #    Q16683; Q16684; Q56II4; Q6GU42; C9J690 [Other Products]
 UniProt Related Accession #    P19801 [Other Products]
 Molecular Weight    87,239 Da
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 NCBI Official Full Name    amiloride-sensitive amine oxidase
 NCBI Official Synonym Full Names    amine oxidase, copper containing 1
 NCBI Official Symbol    AOC1 [Similar Products]
 NCBI Official Synonym Symbols   
ABP; DAO; KAO; ABP1; DAO1
[Similar Products]
 NCBI Protein Information    amiloride-sensitive amine oxidase [copper-containing]; amiloride-sensitive amine oxidase [copper-containing]; histaminase; diamine oxidase; kidney amine oxidase; amiloride-binding protein 1; amine oxidase copper domain-containing protein 1; amiloride binding protein 1 (amine oxidase (copper-containing))
 UniProt Protein Name    Amiloride-sensitive amine oxidase [copper-containing]
 UniProt Synonym Protein Names   
Amiloride-binding protein 1; Amine oxidase copper domain-containing protein 1; Histaminase; Kidney amine oxidase; KAO
 Protein Family    ARS-binding protein
 UniProt Gene Name    AOC1 [Similar Products]
 UniProt Synonym Gene Names    ABP1; DAO1; DAO; Diamine oxidase; KAO [Similar Products]
 UniProt Entry Name    AOC1_HUMAN
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 NCBI Summary for ABP1    This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
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 UniProt Comments for ABP1    ABP1: Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. Belongs to the copper/topaquinone oxidase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; EC 1.4.3.22; Amino Acid Metabolism - histidine; Secreted; Amino Acid Metabolism - tryptophan; Secreted, signal peptide; Amino Acid Metabolism - arginine and proline

Chromosomal Location of Human Ortholog: 7q36.1

Cellular Component: extracellular space; tight junction; plasma membrane; peroxisome

Molecular Function: heparin binding; amine oxidase activity; copper ion binding; protein homodimerization activity; zinc ion binding; protein complex binding; cation channel activity; receptor activity; drug binding; calcium ion binding; sodium channel activity; quinone binding

Biological Process: response to drug; response to antibiotic; amine metabolic process
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 Research Articles on ABP1    1. Serum diamine oxidase levels were influenced by the menstrual cycle.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ABP1 recombinant proteinPathways associated with ABP1 recombinant protein
 Reference Product  PubMed Publications
 DAO recombinant protein  >1 publications with ABP1 and DAO
 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Histidine Metabolism Pathway antibodies  Histidine Metabolism Pathway Diagram
 Histidine Metabolism Pathway antibodies  Histidine Metabolism Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram
 Histamine Degradation Pathway antibodies  Histamine Degradation Pathway Diagram
Diseases associated with ABP1 recombinant proteinOrgans/Tissues associated with ABP1 recombinant protein
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >5 publications with ABP1 and Fibrosis
 Asthma Antibodies  >3 publications with ABP1 and Asthma
 Lung Diseases, Obstructive Antibodies  >2 publications with ABP1 and Lung Diseases, Obstructive
 Nervous System Diseases Antibodies  >2 publications with ABP1 and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >2 publications with ABP1 and Neoplasm Metastasis
 Inflammation Antibodies  >2 publications with ABP1 and Inflammation
 Muscular Diseases Antibodies  >1 publications with ABP1 and Muscular Diseases
 Brain Diseases Antibodies  >1 publications with ABP1 and Brain Diseases
 Drug Toxicity Antibodies  >1 publications with ABP1 and Drug Toxicity
 Drug Hypersensitivity Antibodies  >1 publications with ABP1 and Drug Hypersensitivity
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >14 publications with ABP1 and Blood
 Kidney Antibodies  >9 publications with ABP1 and Kidney
 Liver Antibodies  >5 publications with ABP1 and Liver
 Brain Antibodies  >4 publications with ABP1 and Brain
 Placenta Antibodies  >4 publications with ABP1 and Placenta
 Intestine Antibodies  >3 publications with ABP1 and Intestine
 Muscle Antibodies  >3 publications with ABP1 and Muscle
 Lung Antibodies  >2 publications with ABP1 and Lung
 Thymus Antibodies  >2 publications with ABP1 and Thymus
 Ovary Antibodies  >1 publications with ABP1 and Ovary
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