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IAPP recombinant protein :: Amylin Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS5304623
SDS-PAGE
Unit / Price
0.05 mg  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Amylin (IAPP), Recombinant Protein

★Popular Item★
 Also Known As   

Amylin protein

 Product Synonym Names    Amylin protein; Diabetes associated peptide protein; DAP protein; Insulinoma amyloid peptide protein; Islet amyloid polypeptide protein
 Product Gene Name   

IAPP recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    147940
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 Host    Human
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 Purity/Purification    > 90% pure
 Form/Format    Supplied in liquid form in PBS buffer with 20 mM GSH
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 Protein Type    Recombinant
 Biological Significance    Amylin selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
 Expression System    E Coli
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 Preparation and Storage    Store at 4 degree C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 degree C, avoid repeat freeze/thaw cycles
 Other Notes    Small volumes of IAPP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for IAPP recombinant protein

   Purified recombinant Amylin protein
 Product Categories/Family for IAPP recombinant protein    Nutrition & Metabolism
 Applications Tested/Suitable for IAPP recombinant protein   

ELISA (EIA), SDS-PAGE, Western Blot (WB)

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 SDS-PAGE of IAPP recombinant protein   
IAPP recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for IAPP. It may not necessarily be applicable to this product.
 NCBI GI #    457131
 NCBI GeneID    3375
 NCBI Accession #    AAA35524.1 [Other Products]
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 UniProt Secondary Accession #    Q0ZD87; Q14598 [Other Products]
 UniProt Related Accession #    P10997 [Other Products]
 Molecular Weight    31 kDa [Similar Products]
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 NCBI Official Full Name    amylin, partial
 NCBI Official Synonym Full Names    islet amyloid polypeptide
 NCBI Official Symbol    IAPP [Similar Products]
 NCBI Official Synonym Symbols   
DAP; IAP
[Similar Products]
 NCBI Protein Information    islet amyloid polypeptide
 UniProt Protein Name    Islet amyloid polypeptide
 UniProt Synonym Protein Names   
Amylin; Diabetes-associated peptide; DAP; Insulinoma amyloid peptide
 Protein Family    Islet amyloid polypeptide
 UniProt Gene Name    IAPP [Similar Products]
 UniProt Synonym Gene Names    DAP [Similar Products]
 UniProt Entry Name    IAPP_HUMAN
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 NCBI Summary for IAPP    The protein encoded by this gene is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. This protein also exhibits an bactericidal, antimicrobial activity. [provided by RefSeq, Sep 2014]
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 UniProt Comments for IAPP    IAPP: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. Belongs to the calcitonin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12p12.1

Cellular Component: extracellular space; cell soma; extracellular region

Molecular Function: identical protein binding; hormone activity; receptor binding

Biological Process: negative regulation of cell differentiation; cell-cell signaling; apoptosis; eating behavior; sensory perception of pain; signal transduction; negative regulation of bone resorption; endocrine pancreas development
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 Research Articles on IAPP    1. Plasma levels of IAPP and insulin deviate in a subpopulation of young with newly-diagnosed type 1 diabetes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IAPP recombinant proteinPathways associated with IAPP recombinant protein
 Reference Product  PubMed Publications
 INS recombinant protein  >42 publications with IAPP and INS
 PDX1 recombinant protein  >25 publications with IAPP and PDX1
 GIP recombinant protein  >19 publications with IAPP and GIP
 ADM recombinant protein  >3 publications with IAPP and ADM
 CALCR recombinant protein  >3 publications with IAPP and CALCR
 GCG recombinant protein  >3 publications with IAPP and GCG
 CALCA recombinant protein  >1 publications with IAPP and CALCA
 CALCB recombinant protein  >1 publications with IAPP and CALCB
 Products by Pathway  Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Calcitonin-like Ligand Receptors Pathway antibodies  Calcitonin-like Ligand Receptors Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 Maturity Onset Diabetes Of The Young Pathway antibodies  Maturity Onset Diabetes Of The Young Pathway Diagram
Diseases associated with IAPP recombinant proteinOrgans/Tissues associated with IAPP recombinant protein
 Disease Name  Pubmed Publications
 Diabetes Mellitus Antibodies  >937 publications with IAPP and Diabetes Mellitus
 Diabetes Mellitus, Type 2 Antibodies  >615 publications with IAPP and Diabetes Mellitus, Type 2
 Hyperglycemia Antibodies  >177 publications with IAPP and Hyperglycemia
 Nervous System Diseases Antibodies  >93 publications with IAPP and Nervous System Diseases
 Diabetes Mellitus, Experimental Antibodies  >91 publications with IAPP and Diabetes Mellitus, Experimental
 Inflammation Antibodies  >46 publications with IAPP and Inflammation
 Hypertension Antibodies  >34 publications with IAPP and Hypertension
 Gastrointestinal Diseases Antibodies  >25 publications with IAPP and Gastrointestinal Diseases
 Kidney Diseases Antibodies  >19 publications with IAPP and Kidney Diseases
 Necrosis Antibodies  >16 publications with IAPP and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >819 publications with IAPP and Pancreas
 Connective Tissue Antibodies  >43 publications with IAPP and Connective Tissue
 Mixed Antibodies  >39 publications with IAPP and Mixed
 Testis Antibodies  >1 publications with IAPP and Testis
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