P67885.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
NCBI Official Full Name
Angiotensinogen
UniProt Protein Name
Angiotensinogen
UniProt Synonym Protein Names
Serpin A8Cleaved into the following 3 chains:Angiotensin-1; Alternative name(s):; Angiotensin I; Ang IAngiotensin-2; Alternative name(s):; Angiotensin II; Ang IIAngiotensin-3; Alternative name(s):; Angiotensin III; Ang III; Des-Asp[1]-angiotensin II
UniProt Synonym Gene Names
UniProt Entry Name
ANGT_CHICK
UniProt Comments for AGT
Function: In response to lowered blood pressure, the enzyme renin cleaves angiotensin-1, from angiotensinogen. ACE (angiotensin converting enzyme) then removes a dipeptide to yield the physiologically active peptide angiotensin-2, the most potent pressor substance known, which helps regulate volume and mineral balance of body fluids.
Subcellular location: Secreted.
Tissue specificity: Expressed by the liver and secreted in plasma.
Sequence similarities: Belongs to the serpin family.
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Products associated with AGT recombinant protein
Pathways associated with AGT recombinant protein
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