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Anxa2 recombinant protein :: Annexin A2 (Anxa2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS950991
SDS-PAGE
Unit / Price
0.05 mg (E-Coli)  /  $745 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $865 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,000 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,000 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,100 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,165 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,245 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,270 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,315 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,565 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,825 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,890 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,005 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,430 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Annexin A2 (Anxa2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Annexin A2 (Anxa2)

 Product Synonym Names    Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36
 Product Gene Name   

Anxa2 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Anxa2; Anx2; Cal1h [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-339aa; Full length protein
 Sequence    STVHEILCK LSLEGDHSTP PSAYGSVKPY TNFDAERDAL NIETAVKTKG VDEVTIVNIL TNRSNVQRQD IAFAYQRRTK KELPSALKSA LSGHLETVIL GLLKTPAQYD ASELKASMKG LGTDEDSLIE IICSRTNQEL QEINRVYKEM YKTDLEKDII SDTSGDFRKL MVALAKGRRA EDGSVIDYEL IDQDARELYD AGVKRKGTDV PKWISIMTER SVCHLQKVFE RYKSYSPYDM LESIKKEVKG DLENAFLNLV QCIQNKPLYF ADRLYDSMKG KGTRDKVLIR IMVSRSEVDM LKIRSEFKRK YGKSLYYYIQ QDTKGDYQKA LLYLCGGDD
 3D Structure    ModBase 3D Structure for P07356
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Anxa2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Anxa2 recombinant protein

   Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response (By similarity). Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translationalmechanism but also competes with LDLR for binding with PCSK9 .
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 SDS-PAGE of Anxa2 recombinant protein    Anxa2 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Anxa2. It may not necessarily be applicable to this product.
 NCBI GI #    6996913
 NCBI GeneID    12306
 NCBI Accession #    NP_031611.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_007585.3 [Other Products]
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 UniProt Primary Accession #    P07356 [Other Products]
 UniProt Related Accession #    P07356 [Other Products]
 Molecular Weight    50kD
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 NCBI Official Full Name    annexin A2
 NCBI Official Synonym Full Names    annexin A2
 NCBI Official Symbol    Anxa2 [Similar Products]
 NCBI Official Synonym Symbols   
Cal1h; AW215814
[Similar Products]
 NCBI Protein Information    annexin A2; p36; PAP-IV; annexin-2; protein I; annexin II; lipocortin II; chromobindin 8; chromobindin-8; 33-kDa calcimedin; 36-kDa calelectrin; calpactin I heavy chain; calpactin-1 heavy chain; placental anticoagulant protein IV; 33kDa lymphocyte Ca<2+>- binding protein; 33-kDa lymphocyte Ca<2+>- binding protein
 UniProt Protein Name    Annexin A2
 UniProt Synonym Protein Names   
Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36
 Protein Family    Annexin
 UniProt Gene Name    Anxa2 [Similar Products]
 UniProt Synonym Gene Names    Anx2; Cal1h; PAP-IV [Similar Products]
 UniProt Entry Name    ANXA2_MOUSE
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 UniProt Comments for Anxa2    ANXA2: a calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. Heterotetramer containing 2 light chains of S100A10 2 heavy chains of ANXA2. May cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.

Protein type: Motility/polarity/chemotaxis; Lipid-binding; Calcium-binding

Cellular Component: extrinsic to plasma membrane; extracellular space; protein complex; cell surface; lysosomal membrane; late endosome membrane; early endosome; extracellular region; lipid particle; cell cortex; lipid raft; ruffle; proteinaceous extracellular matrix; membrane; perinuclear region of cytoplasm; cytoplasm; plasma membrane; stress fiber; basement membrane; midbody; cell junction; nucleus; sarcolemma; vesicle; endosome

Molecular Function: phospholipase inhibitor activity; phosphatidylinositol-4,5-bisphosphate binding; protein binding; calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity; cytoskeletal protein binding; calcium ion binding; calcium-dependent protein binding; Rab GTPase binding

Biological Process: fibrinolysis; positive regulation of fibroblast proliferation; collagen fibril organization; negative regulation of catalytic activity; protein heterotetramerization; positive regulation of vesicle fusion; positive regulation of binding; positive regulation of protein amino acid phosphorylation; angiogenesis; body fluid secretion; lipid raft formation; membrane budding
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 Research Articles on Anxa2    1. Plasminogen stimulates autocrine cytokine production in human airway smooth muscle cells in a manner mediated by plasmin and annexin A2.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Anxa2 recombinant proteinDiseases associated with Anxa2 recombinant protein
 Products by Pathway  Pathway Diagram
 Dissolution Of Fibrin Clot Pathway antibodies  Dissolution Of Fibrin Clot Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Prostaglandin Synthesis And Regulation Pathway antibodies  Prostaglandin Synthesis And Regulation Pathway Diagram
 XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway antibodies  XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >95 publications with Anxa2 and Inflammation
 Adenocarcinoma Antibodies  >76 publications with Anxa2 and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >67 publications with Anxa2 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >60 publications with Anxa2 and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >57 publications with Anxa2 and Neoplasm Metastasis
 Necrosis Antibodies  >48 publications with Anxa2 and Necrosis
 Neoplasm Invasiveness Antibodies  >43 publications with Anxa2 and Neoplasm Invasiveness
 Liver Diseases Antibodies  >42 publications with Anxa2 and Liver Diseases
 Brain Diseases Antibodies  >37 publications with Anxa2 and Brain Diseases
 Carcinoma, Squamous Cell Antibodies  >37 publications with Anxa2 and Carcinoma, Squamous Cell
Organs/Tissues associated with Anxa2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >228 publications with Anxa2 and Blood
 Lung Antibodies  >102 publications with Anxa2 and Lung
 Brain Antibodies  >99 publications with Anxa2 and Brain
 Liver Antibodies  >81 publications with Anxa2 and Liver
 Muscle Antibodies  >79 publications with Anxa2 and Muscle
 Kidney Antibodies  >64 publications with Anxa2 and Kidney
 Bone Antibodies  >63 publications with Anxa2 and Bone
 Embryonic Tissue Antibodies  >50 publications with Anxa2 and Embryonic Tissue
 Intestine Antibodies  >38 publications with Anxa2 and Intestine
 Skin Antibodies  >33 publications with Anxa2 and Skin
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