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ANXA3 recombinant protein :: Annexin A3 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS143632 ANXA3 recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $2,235 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Annexin A3 (ANXA3), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Annexin A3

 Product Synonym Names    ANXA3 Human; Annexin A3 Human Recombinant; ANX3; ANXA3; Annexin-III; Lipocortin-3; Lipocortin-III; Annexin-3; Annexin A3; Placental anticoagulant protein III; PAP-III; 35-alpha calcimedin; Inositol 1; 2-cyclic phosphate 2-phosphohydrolase
 Product Gene Name   

ANXA3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MASIWVGHRG TVRDYPDFSP SVDAEAIQKA IRGIGTDEKM LISILTERSN AQRQLIVKEY QAAYGKELKD DLKGDLSGHF EHLMVALVTP PAVFDAKQLK KSMKGAGTNE DALIEILTTR TSRQMKDISQ AYYTVYKKSL GDDISSETSG DFRKALLTLA DGRRDESLKV DEHLAKQDAQ ILYKAGENRW GTDEDKFTEI LCLRSFPQLK LTFDEYRNIS QKDIVDSIKG ELSGHFEDLL LAIVNCVRNT PAFLAERLHR ALKGIGTDEF TLNRIMVSRS EIDLLDIRTE FKKHYGYSLY SAIKSDTSGD YEITLLKICG GDD
 OMIM    106490
 3D Structure    ModBase 3D Structure for P12429
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 Host    E Coli
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE.
 Form/Format    The ANXA3 protein solution contains 20mM Tris-HCl, pH-7.5, 1mM DTT and 10% glycerol.
Sterile filtered colorless solution.
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 Preparation and Storage    Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
 Other Notes    Small volumes of ANXA3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ANXA3 recombinant protein

   Description: ANXA3 produced in E Coli is a single, non-glycosylated polypeptide chain containing 323 amino acids (1-323 a.a.) and having a molecular mass of 36.3 kDa. ANXA3 is purified by proprietary chromatographic techniques.

Introduction: ANXA3 is an inhibitor of phospholipase A2. ANXA3 possesses anti-coagulant properties. ANXA3 cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. ANXA3 is part of the annexin family which are members of the calcium-dependent phospholipid-binding protein family that are involved in the regulation of cellular growth and in signal transduction pathways. ANXA3 takes part as an anti-coagulation factor.
 Product Categories/Family for ANXA3 recombinant protein    RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Annexin
NCBI/Uniprot data below describe general gene information for ANXA3. It may not necessarily be applicable to this product.
 NCBI GI #    4826643
 NCBI GeneID    306
 NCBI Accession #    NP_005130.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005139.2 [Other Products]
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 UniProt Primary Accession #    P12429 [Other Products]
 UniProt Secondary Accession #    Q6LET2; B2R9W6 [Other Products]
 UniProt Related Accession #    P12429 [Other Products]
 Molecular Weight    36,375 Da
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 NCBI Official Full Name    annexin A3
 NCBI Official Synonym Full Names    annexin A3
 NCBI Official Symbol    ANXA3 [Similar Products]
 NCBI Official Synonym Symbols   
ANX3
[Similar Products]
 NCBI Protein Information    annexin A3; 35-alpha calcimedin; Annexin III (lipocortin III); PAP-III; annexin III (lipocortin III, 1,2-cyclic-inositol-phosphate phosphodiesterase, placental anticoagulant protein III, calcimedin 35-alpha); annexin-3; inositol 1,2-cyclic phosphate 2-phosphohydrolase
 UniProt Protein Name    Annexin A3
 UniProt Synonym Protein Names   
35-alpha calcimedin; Annexin III; Annexin-3; Inositol 1,2-cyclic phosphate 2-phosphohydrolase; Lipocortin III; Placental anticoagulant protein III; PAP-III
 Protein Family    Annexin
 UniProt Gene Name    ANXA3 [Similar Products]
 UniProt Synonym Gene Names    ANX3; PAP-III [Similar Products]
 UniProt Entry Name    ANXA3_HUMAN
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 NCBI Summary for ANXA3    This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ANXA3    ANXA3: a calcium/phospholipid-binding protein and inhibitor of phospholipase A2, Possesses anti-coagulant properties. Cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 4q21.21

Cellular Component: specific granule; phagocytic vesicle membrane; membrane; cytoplasm; plasma membrane

Molecular Function: calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity; calcium ion binding; calcium-dependent protein binding

Biological Process: positive regulation of angiogenesis; negative regulation of catalytic activity; neutrophil degranulation; defense response to bacterium; positive regulation of transcription factor activity; phagocytosis
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 Research Articles on ANXA3    1. Expression of annexin A3 was increased in gastric cancer compared with that in normal gastric tissues. Annexin A3 expression was significantly associated with tumor volume and TNM stage.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ANXA3 recombinant proteinPathways associated with ANXA3 recombinant protein
 Reference Product  PubMed Publications
 ANXA1 recombinant protein  >1 publications with ANXA3 and ANXA1
 Products by Pathway  Pathway Diagram
 Prostaglandin Synthesis And Regulation Pathway antibodies  Prostaglandin Synthesis And Regulation Pathway Diagram
Diseases associated with ANXA3 recombinant proteinOrgans/Tissues associated with ANXA3 recombinant protein
 Disease Name  Pubmed Publications
 Prostatic Neoplasms Antibodies  >9 publications with ANXA3 and Prostatic Neoplasms
 Nervous System Diseases Antibodies  >6 publications with ANXA3 and Nervous System Diseases
 Inflammation Antibodies  >5 publications with ANXA3 and Inflammation
 Brain Diseases Antibodies  >4 publications with ANXA3 and Brain Diseases
 Lung Neoplasms Antibodies  >4 publications with ANXA3 and Lung Neoplasms
 Liver Diseases Antibodies  >4 publications with ANXA3 and Liver Diseases
 Kidney Diseases Antibodies  >3 publications with ANXA3 and Kidney Diseases
 Arthritis, Rheumatoid Antibodies  >3 publications with ANXA3 and Arthritis, Rheumatoid
 Disease Models, Animal Antibodies  >3 publications with ANXA3 and Disease Models, Animal
 Pancreatic Neoplasms Antibodies  >3 publications with ANXA3 and Pancreatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >16 publications with ANXA3 and Blood
 Prostate Antibodies  >10 publications with ANXA3 and Prostate
 Liver Antibodies  >8 publications with ANXA3 and Liver
 Brain Antibodies  >5 publications with ANXA3 and Brain
 Lung Antibodies  >4 publications with ANXA3 and Lung
 Kidney Antibodies  >3 publications with ANXA3 and Kidney
 Vascular Antibodies  >3 publications with ANXA3 and Vascular
 Lymph Node Antibodies  >2 publications with ANXA3 and Lymph Node
 Heart Antibodies  >2 publications with ANXA3 and Heart
 Embryonic Tissue Antibodies  >1 publications with ANXA3 and Embryonic Tissue
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