NP_001139438.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
proliferation marker protein Ki-67 isoform 2
NCBI Official Synonym Full Names
marker of proliferation Ki-67
NCBI Protein Information
proliferation marker protein Ki-67; antigen KI-67
UniProt Protein Name
Proliferation marker protein Ki-67
UniProt Synonym Protein Names
Antigen identified by monoclonal antibody Ki-67
UniProt Synonym Gene Names
NCBI Summary for KI67
This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]
UniProt Comments for KI67
KI-67: a protein that may be a marker of proliferating cells, involved in chromatin compaction. Its expression is altered in many tumor types including osteosarcomas, histiocytomas, prostate, breast and esophageal cancers. Mutated in colon, cervical and lung cancers.
Protein type: Cell cycle regulation; Nucleolus
Chromosomal Location of Human Ortholog: 10q26.2
Cellular Component: condensed chromosome; membrane; nuclear body; nucleolus; nucleus
Molecular Function: protein binding; protein C-terminus binding; RNA binding
Biological Process: cell proliferation; regulation of chromosome segregation; regulation of mitosis
Research Articles on KI67
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Products associated with KI67 recombinant protein
Diseases associated with KI67 recombinant protein
Organs/Tissues associated with KI67 recombinant protein
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