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CD1D recombinant protein :: Antigen-presenting glycoprotein CD1d Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS960119
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Antigen-presenting glycoprotein CD1d, Recombinant Protein

 Also Known As   

Recombinant Human Antigen-presenting glycoprotein CD1d

 Product Synonym Names    R3G1; CD1d
 Product Gene Name   

CD1D recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    20-301aa; Extracellular Domain
 OMIM    188410
 3D Structure    ModBase 3D Structure for P15813
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CD1D recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CD1D recombinant protein

   Antigen-presenting protein that binds self and non-self glycolipids and presents th to T-cell receptors on natural killer T-cells.
 Product Categories/Family for CD1D recombinant protein    Immunology
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 SDS-PAGE of CD1D recombinant protein    CD1D recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for CD1D. It may not necessarily be applicable to this product.
 NCBI GI #    4502649
 NCBI GeneID    912
 NCBI Accession #    NP_001757.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001766.3 [Other Products]
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 UniProt Primary Accession #    P15813 [Other Products]
 UniProt Secondary Accession #    Q5W0J3; Q9UMM3; Q9Y5M4; D3DVD5 [Other Products]
 UniProt Related Accession #    P15813 [Other Products]
 Molecular Weight    47.9kD
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 NCBI Official Full Name    antigen-presenting glycoprotein CD1d isoform 1
 NCBI Official Synonym Full Names    CD1d molecule
 NCBI Official Symbol    CD1D [Similar Products]
 NCBI Official Synonym Symbols   
R3; CD1A; R3G1
[Similar Products]
 NCBI Protein Information    antigen-presenting glycoprotein CD1d
 UniProt Protein Name    Antigen-presenting glycoprotein CD1d
 UniProt Synonym Protein Names   
R3G1; CD_antigen: CD1d
 Protein Family    Antigen-presenting glycoprotein
 UniProt Gene Name    CD1D [Similar Products]
 UniProt Entry Name    CD1D_HUMAN
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 NCBI Summary for CD1D    This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
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 UniProt Comments for CD1D    CD1D: Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.

Protein type: Cell surface; Membrane protein, integral; Apoptosis; Lipid-binding

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: basolateral plasma membrane; cell surface; cytoplasm; endoplasmic reticulum membrane; endosome membrane; integral to plasma membrane; lysosomal membrane

Molecular Function: beta-2-microglobulin binding; cell adhesion molecule binding; endogenous lipid antigen binding; exogenous lipid antigen binding; histone binding; lipid antigen binding; receptor activity

Biological Process: antigen processing and presentation, endogenous lipid antigen via MHC class Ib; antigen processing and presentation, exogenous lipid antigen via MHC class Ib; detection of bacterium; heterotypic cell-cell adhesion; innate immune response; positive regulation of innate immune response; positive regulation of T cell proliferation; T cell selection; viral reproduction
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Product References and Citations for CD1D recombinant protein

   Two classes of CD1 genes.Calabi F., Jarvis J.M., Martin L., Milstein C.Eur. J. Immunol. 19:285-292(1989) Isolation and characterization of a cDNA and gene coding for a fourth CD1 molecule.Balk S.P., Bleicher P.A., Terhorst C.Proc. Natl. Acad. Sci. U.S.A. 86:252-256(1989) The DNA sequence and biological annotation of human chromosome 1.Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.Nature 441:315-321(2006)
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 Research Articles on CD1D    1. High CD1d expression is associated with medulloblastomas.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CD1D recombinant proteinPathways associated with CD1D recombinant protein
 Reference Product  PubMed Publications
 CD4 recombinant protein  >437 publications with CD1D and CD4
 KLRB1 recombinant protein  >19 publications with CD1D and KLRB1
 LEF1 recombinant protein  >2 publications with CD1D and LEF1
 CD74 recombinant protein  >1 publications with CD1D and CD74
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
Diseases associated with CD1D recombinant proteinOrgans/Tissues associated with CD1D recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >263 publications with CD1D and Inflammation
 Disease Models, Animal Antibodies  >235 publications with CD1D and Disease Models, Animal
 Liver Diseases Antibodies  >128 publications with CD1D and Liver Diseases
 Necrosis Antibodies  >105 publications with CD1D and Necrosis
 Neoplasms, Experimental Antibodies  >67 publications with CD1D and Neoplasms, Experimental
 Skin Diseases Antibodies  >61 publications with CD1D and Skin Diseases
 Brain Diseases Antibodies  >60 publications with CD1D and Brain Diseases
 Arthritis, Experimental Antibodies  >31 publications with CD1D and Arthritis, Experimental
 Kidney Diseases Antibodies  >28 publications with CD1D and Kidney Diseases
 Fatty Liver Antibodies  >23 publications with CD1D and Fatty Liver
 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >257 publications with CD1D and Spleen
 Thymus Antibodies  >176 publications with CD1D and Thymus
 Lung Antibodies  >111 publications with CD1D and Lung
 Lymph Node Antibodies  >89 publications with CD1D and Lymph Node
 Intestine Antibodies  >80 publications with CD1D and Intestine
 Skin Antibodies  >61 publications with CD1D and Skin
 Kidney Antibodies  >37 publications with CD1D and Kidney
 Pancreas Antibodies  >25 publications with CD1D and Pancreas
 Brain Antibodies  >25 publications with CD1D and Brain
 Heart Antibodies  >20 publications with CD1D and Heart
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