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Iap2 recombinant protein :: Apoptosis 2 inhibitor (Iap2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1438880 Iap2 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $920 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,125 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,230 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,350 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,360 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,375 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,430 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,525 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,930 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,045 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,075 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,320 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,690 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Apoptosis 2 inhibitor (Iap2), Recombinant Protein

 Also Known As   

Recombinant Drosophila melanogaster Apoptosis 2 inhibitor (Iap2)

 Product Gene Name   

Iap2 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Iap2 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-498aa, full length protein
 Sequence    MTELGMELES VRLATFGEWP LNAPVSAEDL VANGFFATGN WLEAECHFCH VRIDRWEYGD QVAERHRRSS PICSMVLAPN HCGNVPRSQE SDNEGNSVVD SPESCSCPDL LLEANRLVTF KDWPNPNITP QALAKAGFYY LNRLDHVKCV WCNGVIAKWE KNDNAFEEHK RFFPQCPRVQ MGPLIEFATG KNLDELGIQP TTLPLRPKYA CVDARLRTFT DWPISNIQPA SALAQAGLYY QKIGDQVRCF HCNIGLRSWQ KEDEPWFEHA KWSPKCQFVL LAKGPAYVSE VLATTAANAS SQPATAPAPT LQADVLMDEA PAKEALALGI DGGVVRNAIQ RKLLSSGCAF STLDELLHDI FDDAGAGAAL EVREPPEPSA PFIEPCQATT SKAASVPIPV ADSIPAKPQA AEAVANISKI TDEIQKMSVA TPNGNLSLEE ENRQLKDARL CKVCLDEEVG VVFLPCGHLA TCNQCAPSVA NCPMCRADIK GFVRTFLS
 3D Structure    ModBase 3D Structure for Q24307
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Drosophila melanogaster (Fruit fly)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Iap2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Iap2. It may not necessarily be applicable to this product.
 NCBI GI #    17137140
 NCBI GeneID    36748
 NCBI Accession #    NP_477127.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_057779.5 [Other Products]
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 UniProt Primary Accession #    Q24307 [Other Products]
 UniProt Secondary Accession #    Q24115; Q24149; Q24177; Q960U3; Q9V7G1; A4UZI4 [Other Products]
 UniProt Related Accession #    Q24307 [Other Products]
 Molecular Weight    54,538 Da
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 NCBI Official Full Name    Death-associated inhibitor of apoptosis 2, isoform A
 NCBI Official Synonym Full Names    Death-associated inhibitor of apoptosis 2
 NCBI Official Symbol    Diap2 [Similar Products]
 NCBI Official Synonym Symbols   
CG8293; D-iap2; D-IAP2; dIAP; Diap; DIAP; Diap-2; DIAP-2; diap2; dIAP2; DIAP2; DIAPII; Diha; DIHA; dILP; DmelCG8293; IAP; Iap2; IAP2; Ilp
[Similar Products]
 NCBI Protein Information    CG8293 gene product from transcript CG8293-RB
 UniProt Protein Name    Death-associated inhibitor of apoptosis 2
 UniProt Synonym Protein Names   
Apoptosis 2 inhibitor; IAP homolog A; IAP-like protein; ILP; dILP; Inhibitor of apoptosis 2
 Protein Family    Probable apoptosis inhibitor
 UniProt Gene Name    Diap2 [Similar Products]
 UniProt Synonym Gene Names    DIHA; Iap2; Ilp; ILP; dILP [Similar Products]
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 UniProt Comments for Iap2    Required for activation of NF-kappaB transcription factors in the immune deficiency (Imd) signaling cascade which is essential for innate immune responses upon infection by Gram-negative bacteria (PubMed:16894030, PubMed:17068333). Promotes cytoplasmic cleavage of Rel and its translocation to the nucleus where it drives expression of antimicrobial peptides (PubMed:17068333, PubMed:24374974). Binds, polyubiquitinates and activates Dredd which is required for Rel-mediated induction of antimicrobial peptides (PubMed:22549468). Anti-apoptotic protein which binds, ubiquitinates and inactivates the effector caspase Drice (PubMed:18166655). Suppresses rpr and hid-dependent cell death in the eye (PubMed:8548811). However, has also been shown to have little, if any, role in the regulation of the canonical caspase-dependent apoptosis pathway (PubMed:17068333). Plays a role in regulating the expression of ion channels (PubMed:24374974).
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 Research Articles on Iap2    1. cleaved protein retains the ability to interact with immune deficiency pathway signal transduction
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Iap2 recombinant proteinDiseases associated with Iap2 recombinant protein
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway antibodies  RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By WNT In Cancer Pathway antibodies  Signaling By WNT In Cancer Pathway Diagram
 Signaling By Wnt Pathway antibodies  Signaling By Wnt Pathway Diagram
 TCF Dependent Signaling In Response To WNT Pathway antibodies  TCF Dependent Signaling In Response To WNT Pathway Diagram
 Ubiquitin Mediated Proteolysis Pathway antibodies  Ubiquitin Mediated Proteolysis Pathway Diagram
 Disease Name  Pubmed Publications
 Lymphatic Diseases Antibodies  >17 publications with Iap2 and Lymphatic Diseases
 Genital Diseases, Male Antibodies  >8 publications with Iap2 and Genital Diseases, Male
 Prostatic Diseases Antibodies  >5 publications with Iap2 and Prostatic Diseases
 Herpesviridae Infections Antibodies  >4 publications with Iap2 and Herpesviridae Infections
 Epstein-Barr Virus Infections Antibodies  >4 publications with Iap2 and Epstein-Barr Virus Infections
 Immunologic Deficiency Syndromes Antibodies  >2 publications with Iap2 and Immunologic Deficiency Syndromes
 Metaplasia Antibodies  >2 publications with Iap2 and Metaplasia
 Gonadal Disorders Antibodies  >2 publications with Iap2 and Gonadal Disorders
 Bone Diseases Antibodies  >2 publications with Iap2 and Bone Diseases
 Ovarian Diseases Antibodies  >1 publications with Iap2 and Ovarian Diseases
Organs/Tissues associated with Iap2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >3 publications with Iap2 and Testis
 Embryonic Tissue Antibodies  >2 publications with Iap2 and Embryonic Tissue
 Head Antibodies  >2 publications with Iap2 and Head
 Ovary Antibodies  >1 publications with Iap2 and Ovary
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