NP_499284.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
31,824 Da
NCBI Official Full Name
Apoptosis regulator ced-9
NCBI Protein Information
Apoptosis regulator ced-9
UniProt Protein Name
Apoptosis regulator ced-9
UniProt Synonym Protein Names
Cell death protein 9
UniProt Comments for ced-9
Plays a major role in programmed cell death (PCD, apoptosis) (PubMed:7907274, PubMed:10688797). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3 (PubMed:9024666, PubMed:9027313, PubMed:9604928, PubMed:12894216, PubMed:15383288, PubMed:16208361). During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway (PubMed:26074078).
Research Articles on ced-9
Precautions
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Disclaimer
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Products associated with ced-9 recombinant protein
Pathways associated with ced-9 recombinant protein
Diseases associated with ced-9 recombinant protein
Disease Name |
Pubmed Publications |
Death Antibodies |
>166 publications with ced-9 and Death |
Necrosis Antibodies |
>9 publications with ced-9 and Necrosis |
Nervous System Diseases Antibodies |
>8 publications with ced-9 and Nervous System Diseases |
Lymphoma, Non-Hodgkin Antibodies |
>3 publications with ced-9 and Lymphoma, Non-Hodgkin |
Congenital Abnormalities Antibodies |
>2 publications with ced-9 and Congenital Abnormalities |
Congenital, Hereditary, and Neonatal Diseases and Abnormalities Antibodies |
>2 publications with ced-9 and Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
Hypersensitivity Antibodies |
>2 publications with ced-9 and Hypersensitivity |
Disease Models, Animal Antibodies |
>1 publications with ced-9 and Disease Models, Animal |
Infertility, Male Antibodies |
>1 publications with ced-9 and Infertility, Male |
Infertility Antibodies |
>1 publications with ced-9 and Infertility |
Organs/Tissues associated with ced-9 recombinant protein
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