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AQP3 recombinant protein :: Aquaporin-3 (AQP3) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS7007875 AQP3 recombinant protein
Unit / Price
0.01 mg  /  $925 +1 FREE 8GB USB
0.05 mg  /  $1,425 +1 FREE 8GB USB
0.1 mg  /  $2,350 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Aquaporin-3 (AQP3), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Aquaporin-3 (AQP3)

 Product Gene Name   

AQP3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS7007875 COA    COA PDF
 Sequence Positions    1-292aa; full length protein
 Sequence    MGRQKELVSR CGEMLHIRYR LLRQALAECL GTLILVMFGC GSVAQVVLSR GTHGGFLTIN LAFGFAVTLG ILIAGQVSGA HLNPAVTFAM CFLAREPWIK LPIYTLAQTL GAFLGAGIVF GLYYDAIWHF ADNQLFVSGP NGTAGIFATY PSGHLDMING FFDQFIGTAS LIVCVLAIVD PYNNPVPRGL EAFTVGLVVL VIGTSMGFNS GYAVNPARDF GPRLFTALAG WGSAVFTTGQ HWWWVPIVSP LLGSIAGVFV YQLMIGCHLE QPPPSNEEEN VKLAHVKHKE QI
 OMIM    600170
 3D Structure    ModBase 3D Structure for Q92482
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 Host    Cell Free Expression
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 Form/Format    Liquid containing glycerol
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol.
 Tag Information    Tag type will be determined during the manufacturing process.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of AQP3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for AQP3 recombinant protein    Transmembrane Protein
 Application Notes for AQP3 recombinant protein    This is a recombinant transmembrane protein expressed in a cell-free expression system.
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NCBI/Uniprot data below describe general gene information for AQP3. It may not necessarily be applicable to this product.
 NCBI GI #    970259826
 NCBI GeneID    360
 NCBI Accession #    NP_001305073.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001318144.1 [Other Products]
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 UniProt Primary Accession #    Q92482 [Other Products]
 UniProt Secondary Accession #    O00108; Q6FGT2; Q6FGW6; A8K843; B2RE16; D3DRL3 [Other Products]
 UniProt Related Accession #    Q92482 [Other Products]
 Molecular Weight    29,987 Da
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 NCBI Official Full Name    aquaporin-3 isoform 2
 NCBI Official Synonym Full Names    aquaporin 3 (Gill blood group)
 NCBI Official Symbol    AQP3 [Similar Products]
 NCBI Official Synonym Symbols   
GIL; AQP-3
[Similar Products]
 NCBI Protein Information    aquaporin-3
 UniProt Protein Name    Aquaporin-3
 UniProt Synonym Protein Names   
Aquaglyceroporin-3
 Protein Family    Aquaporin
 UniProt Gene Name    AQP3 [Similar Products]
 UniProt Synonym Gene Names    AQP-3 [Similar Products]
 UniProt Entry Name    AQP3_HUMAN
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 NCBI Summary for AQP3    This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
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 UniProt Comments for AQP3    AQP3: Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism. Belongs to the MIP/aquaporin (TC 1.A.8) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, misc.; Membrane protein, integral; Membrane protein, multi-pass; Transporter, aquaporin family; Transporter

Chromosomal Location of Human Ortholog: 9p13

Cellular Component: basolateral plasma membrane; cytoplasm; integral to membrane; integral to plasma membrane; intercellular junction; nucleus; plasma membrane

Molecular Function: glycerol channel activity; transporter activity; urea transmembrane transporter activity; water channel activity

Biological Process: cellular water homeostasis; excretion; glycerol transport; odontogenesis; positive regulation of immune system process; regulation of keratinocyte differentiation; renal water homeostasis; response to calcium ion; response to retinoic acid; response to vitamin D; transport; water transport

Disease: Gil Blood Group
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 Research Articles on AQP3    1. the human aquaglyceroporins, i.e., AQP3, AQP7, AQP9 and AQP10 can act as silicon transporters in both Xenopus laevis oocytes and HEK-293 cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with AQP3 recombinant proteinDiseases associated with AQP3 recombinant protein
 Products by Pathway  Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Passive Transport By Aquaporins Pathway antibodies  Passive Transport By Aquaporins Pathway Diagram
 Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway antibodies  Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Vasopressin Regulates Renal Water Homeostasis Via Aquaporins Pathway antibodies  Vasopressin Regulates Renal Water Homeostasis Via Aquaporins Pathway Diagram
 Vasopressin-regulated Water Reabsorption Pathway antibodies  Vasopressin-regulated Water Reabsorption Pathway Diagram
 Vasopressin-regulated Water Reabsorption Pathway antibodies  Vasopressin-regulated Water Reabsorption Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >57 publications with AQP3 and Kidney Diseases
 Disease Models, Animal Antibodies  >50 publications with AQP3 and Disease Models, Animal
 Edema Antibodies  >27 publications with AQP3 and Edema
 Cardiovascular Diseases Antibodies  >24 publications with AQP3 and Cardiovascular Diseases
 Inflammation Antibodies  >22 publications with AQP3 and Inflammation
 Nervous System Diseases Antibodies  >15 publications with AQP3 and Nervous System Diseases
 Liver Diseases Antibodies  >15 publications with AQP3 and Liver Diseases
 Carcinoma, Squamous Cell Antibodies  >15 publications with AQP3 and Carcinoma, Squamous Cell
 Lung Diseases Antibodies  >14 publications with AQP3 and Lung Diseases
 Fibrosis Antibodies  >14 publications with AQP3 and Fibrosis
Organs/Tissues associated with AQP3 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >233 publications with AQP3 and Kidney
 Blood Antibodies  >139 publications with AQP3 and Blood
 Skin Antibodies  >93 publications with AQP3 and Skin
 Lung Antibodies  >61 publications with AQP3 and Lung
 Liver Antibodies  >55 publications with AQP3 and Liver
 Intestine Antibodies  >52 publications with AQP3 and Intestine
 Brain Antibodies  >48 publications with AQP3 and Brain
 Eye Antibodies  >38 publications with AQP3 and Eye
 Salivary Gland Antibodies  >29 publications with AQP3 and Salivary Gland
 Heart Antibodies  >29 publications with AQP3 and Heart
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