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Arg2 recombinant protein :: Arginase II Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2031267 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) Arg2 recombinant protein
Unit / Price
0.01 mg  /  $145 +1 FREE 8GB USB
0.05 mg  /  $270 +1 FREE 8GB USB
0.1 mg  /  $420 +1 FREE 8GB USB
0.2 mg  /  $515 +1 FREE 8GB USB
0.5 mg  /  $995 +1 FREE 8GB USB
1 mg  /  $1,480 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Arginase II (Arg2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Arginase II (Arg2)

 Product Gene Name   

Arg2 recombinant protein

[Similar Products]
 Matching Pairs    Antibody: Arginase II (Arg2) (MBS2004437)
Antigen: Arginase II (MBS2031267)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHS GSEF-VHSVA IVG APFSRGQKKL GVEYGPAAIR EAGLLKRLSR LGCHLKDFGD LSFTNVPQDD PYNNLVVYPR SVGLANQELA EVVSRAVSGG YSCVTMGGDH SLAIGTIIGH ARHRPDLCVI WVDAHADINT PLTTVSGNIH GQPLSFLIKE LQDKVPQLPG FSWIKPCLSP PNIVYIGLRD VEPPEHFILK NYDIQYFSMR EIDRLGIQKV MEQTFDRLIG KRQRPIHLSF DIDAFDPKLA PATGTPVVGG LTYREGVYIT EEIHNTGLLS ALDLVEVNPH LATSEEEAKA TARLAVDVIA SSFGQTREGG HIVYDHLPTP SSPHESENEE CVRI
 OMIM    107830
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 Host    Host: E Coli
Source: Prokaryotic expression
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 Purity/Purification    >95%
 Form/Format    Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
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 Predicted Molecular Mass    37.9kDa
 Accurate Molecular Mass (KD)    66kDa
 Endotoxin    <1.0EU per 1ug (determined by the LAL method)
 Expression System    Prokaryotic expression
 Tag    N-terminal His-Tag
 Organism Species    Mus musculus (Mouse)
 Fragment    Val23~Ile354
 Usage    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of Arg2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for Arg2 recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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NCBI/Uniprot data below describe general gene information for Arg2. It may not necessarily be applicable to this product.
 NCBI GI #    1763758
 NCBI GeneID    384
 NCBI Accession #    AAB39855.1 [Other Products]
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 UniProt Secondary Accession #    Q6FHY8; B2R690 [Other Products]
 UniProt Related Accession #    P78540 [Other Products]
 Molecular Weight    38,578 Da
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 NCBI Official Full Name    arginase II
 NCBI Official Synonym Full Names    arginase 2
 NCBI Official Symbol    ARG2 [Similar Products]
 NCBI Protein Information    arginase-2, mitochondrial
 UniProt Protein Name    Arginase-2, mitochondrial
 UniProt Synonym Protein Names   
Kidney-type arginase; Non-hepatic arginase; Type II arginase
 Protein Family    Arginase
 UniProt Gene Name    ARG2 [Similar Products]
 UniProt Entry Name    ARGI2_HUMAN
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 NCBI Summary for Arg2    Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for Arg2    ARG2: May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders. Belongs to the arginase family.

Protein type: EC 3.5.3.1; Amino Acid Metabolism - arginine and proline; Hydrolase; Mitochondrial

Chromosomal Location of Human Ortholog: 14q24.1

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: metal ion binding; arginase activity

Biological Process: striated muscle contraction; arginine metabolic process; ureteric bud development; nitric oxide biosynthetic process; urea cycle
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 Research Articles on Arg2    1. high fat diet enhanced arginase-II expression/activity and p38mapk activity, which was associated with eNOS-uncoupling as revealed by decreased nitric oxide
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Arg2 recombinant proteinPathways associated with Arg2 recombinant protein
 Reference Product  PubMed Publications
 NOS3 recombinant protein  >20 publications with Arg2 and NOS3
 NOS2 recombinant protein  >16 publications with Arg2 and NOS2
 NOS1 recombinant protein  >10 publications with Arg2 and NOS1
 OAT recombinant protein  >5 publications with Arg2 and OAT
 OTC recombinant protein  >2 publications with Arg2 and OTC
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine Biosynthesis Pathway antibodies  Arginine Biosynthesis Pathway Diagram
 Arginine Biosynthesis Pathway antibodies  Arginine Biosynthesis Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Antibiotics Pathway antibodies  Biosynthesis Of Antibiotics Pathway Diagram
 L-arginine Degradation I (arginase Pathway) antibodies  L-arginine Degradation I (arginase Pathway) Diagram
Diseases associated with Arg2 recombinant proteinOrgans/Tissues associated with Arg2 recombinant protein
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >30 publications with Arg2 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >24 publications with Arg2 and Cardiovascular Diseases
 Inflammation Antibodies  >22 publications with Arg2 and Inflammation
 Nervous System Diseases Antibodies  >22 publications with Arg2 and Nervous System Diseases
 Lung Diseases Antibodies  >18 publications with Arg2 and Lung Diseases
 Brain Diseases Antibodies  >17 publications with Arg2 and Brain Diseases
 Hypertension Antibodies  >12 publications with Arg2 and Hypertension
 Asthma Antibodies  >12 publications with Arg2 and Asthma
 Kidney Diseases Antibodies  >10 publications with Arg2 and Kidney Diseases
 Heart Diseases Antibodies  >8 publications with Arg2 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >76 publications with Arg2 and Blood
 Brain Antibodies  >65 publications with Arg2 and Brain
 Vascular Antibodies  >47 publications with Arg2 and Vascular
 Muscle Antibodies  >42 publications with Arg2 and Muscle
 Kidney Antibodies  >32 publications with Arg2 and Kidney
 Lung Antibodies  >26 publications with Arg2 and Lung
 Intestine Antibodies  >24 publications with Arg2 and Intestine
 Liver Antibodies  >24 publications with Arg2 and Liver
 Heart Antibodies  >22 publications with Arg2 and Heart
 Pituitary Gland Antibodies  >22 publications with Arg2 and Pituitary Gland
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