NP_000653.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,899 Da
NCBI Official Full Name
arylamine N-acetyltransferase 1 isoform a
NCBI Official Synonym Full Names
N-acetyltransferase 1
NCBI Protein Information
arylamine N-acetyltransferase 1
UniProt Protein Name
Arylamine N-acetyltransferase 1
UniProt Synonym Protein Names
Arylamide acetylase 1; Monomorphic arylamine N-acetyltransferase; MNAT; N-acetyltransferase type 1; NAT-1
UniProt Synonym Gene Names
NCBI Summary for NAT1
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
UniProt Comments for NAT1
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.
Research Articles on NAT1
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Products associated with NAT1 recombinant protein
Pathways associated with NAT1 recombinant protein
Diseases associated with NAT1 recombinant protein
Organs/Tissues associated with NAT1 recombinant protein
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