NP_034454.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Predicted Molecular Mass: 47.5kDa Accurate Molecular Mass: 43kDa as determined by SDS-PAGE reducing conditions.
NCBI Official Full Name
aspartate aminotransferase, cytoplasmic
NCBI Official Synonym Full Names
glutamate oxaloacetate transaminase 1, soluble
NCBI Protein Information
aspartate aminotransferase, cytoplasmic; transaminase A; cysteine transaminase, cytoplasmic; cytosolic aspartate aminotransferase; cysteine aminotransferase, cytoplasmic
UniProt Protein Name
Aspartate aminotransferase, cytoplasmic
UniProt Synonym Protein Names
Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; cCAT; Glutamate oxaloacetate transaminase 1; Transaminase A
UniProt Synonym Gene Names
UniProt Entry Name
AATC_MOUSE
UniProt Comments for AST
GOT1: Plays a key role in amino acid metabolism. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein type: EC 2.6.1.1; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - alanine, aspartate and glutamate; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - cysteine and methionine; Transferase; EC 2.6.1.3; Amino Acid Metabolism - phenylalanine, tyrosine and tryptophan biosynthesis
Cellular Component: lysosome; cytoplasm; nerve terminal; nucleus; cytosol
Molecular Function: transferase activity; cysteine transaminase activity; phosphatidylserine decarboxylase activity; carboxylic acid binding; aspartate transaminase activity; transaminase activity; catalytic activity; pyridoxal phosphate binding
Biological Process: amino acid metabolic process; dicarboxylic acid metabolic process; oxaloacetate metabolic process; glycerol biosynthetic process; glutamate catabolic process to aspartate; fatty acid homeostasis; aspartate biosynthetic process; biosynthetic process; aspartate metabolic process; aspartate catabolic process; glutamate catabolic process to 2-oxoglutarate; amino acid biosynthetic process
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Products associated with AST recombinant protein
Pathways associated with AST recombinant protein
Diseases associated with AST recombinant protein
Organs/Tissues associated with AST recombinant protein
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