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Add To Compare List BTLA recombinant protein :: B And T Lymphocyte Associated Recombinant Protein Catalog # MBS147294 Unit / Price 0.002 mg / $245 +1 FREE 8GB USB 0.01 mg / $320 +1 FREE 8GB USB 1 mg / $5,350 +6 FREE 8GB USB 5x1 mg / $23,735 +10 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name B And T Lymphocyte Associated (BTLA), Recombinant Protein Full Product Name Recombinant Human B And T Lymphocyte Associated Product Synonym Names B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; CD272; B And T Lymphocyte Associated; B- And T-Lymphocyte-Associated Protein; B- And T; Lymphocyte Attenuator; CD272 Antigen; BTLA1; BTLA Human; B And T Lymphocyte Associated Human Recombinant Product Gene Name BTLA recombinant protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence ADP KESCDVQ LYIKRQSEHS ILAGDPFELE CPVKYCANRP HVTWCKLNGT TCVKLEDRQT SWKEEKNISF FILHFEPVLP NDNGSYRCSA NFQSNLIESH STTLYVTDVK SASERPSKDE MASRPWLLYS HHHHHH OMIM AY293286 mRNA 3D Structure ModBase 3D Structure for Q7Z6A9 Host Sf9, Insect cells Purity/Purification Greater than 90.0% as determined by SDS-PAGE Form/Format Sterile filtered colorless solutionProtein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol Preparation and Storage Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles Other Notes Small volumes of BTLA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for BTLA recombinant protein Description: BTLA produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 136 amino acids (31-157 a.a.) and having a molecular mass of 15.7kDa (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). BTLA is expressed with an 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.Introduction: NECTIN3, also known as Nectin Cell Adhesion Molecule 3, is part of the nectin family. NECTIN3 is intended to initiate cell-cell adhesion to stimulate cell attachment and to allow subsequent formation of JAM-and cadherin-based intercellular junctions. NECTIN3 induces endocytosis-mediated down-regulation of PVR from the cell surface, which results in reduction of cell movement & proliferation. Following Nectin-3 activity adds strength to the junction through trans-interaction with various molecules. . Product Categories/Family for BTLA recombinant protein Recombinant & Natural Proteins; Recombinant Proteins; Other; BTLA Human NCBI/Uniprot data below describe general gene information for BTLA. It may not necessarily be applicable to this product. NCBI GI # 296439425 NCBI GeneID 151888 NCBI Accession # Q7Z6A9.3 [Other Products] UniProt Primary Accession # Q7Z6A9 [Other Products] UniProt Secondary Accession # Q3B831; Q3HS85; Q6ZNH9[Other Products] UniProt Related Accession # Q7Z6A9[Other Products] Molecular Weight 27,317 Da TOP NCBI Official Full Name B- and T-lymphocyte attenuator NCBI Official Synonym Full Names B and T lymphocyte associated NCBI Official Symbol BTLA [Similar Products] NCBI Official Synonym Symbols BTLA1; CD272 [Similar Products] NCBI Protein Information B- and T-lymphocyte attenuator UniProt Protein Name B- and T-lymphocyte attenuator UniProt Synonym Protein Names B- and T-lymphocyte-associated protein; CD_antigen: CD272 Protein Family B- and T-lymphocyte attenuator UniProt Gene Name BTLA [Similar Products] TOP NCBI Summary for BTLA This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011] TOP UniProt Comments for BTLA Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response. Research Articles on BTLA 1. The percentage of circulating BTLA+CD4+ lymphocytes was significantly higher in patients with severe community acquired pneumonia. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with BTLA recombinant protein Reference Product PubMed Publications TNFRSF14 recombinant protein >73 publications with BTLA and TNFRSF14 CTLA4 recombinant protein >41 publications with BTLA and CTLA4 PDCD1 recombinant protein >34 publications with BTLA and PDCD1 TNFSF14 recombinant protein >13 publications with BTLA and TNFSF14 CD274 recombinant protein >4 publications with BTLA and CD274 VTCN1 recombinant protein >4 publications with BTLA and VTCN1 PTPN6 recombinant protein >3 publications with BTLA and PTPN6 PTPN11 recombinant protein >3 publications with BTLA and PTPN11 Pathways associated with BTLA recombinant protein Products by Pathway Pathway Diagram Adaptive Immune System Pathway antibodies Adaptive Immune System Pathway Diagram Costimulation By The CD28 Family Pathway antibodies Costimulation By The CD28 Family Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Diseases associated with BTLA recombinant protein Disease Name Pubmed Publications Necrosis Antibodies >82 publications with BTLA and Necrosis Immune System Diseases Antibodies >62 publications with BTLA and Immune System Diseases Inflammation Antibodies >35 publications with BTLA and Inflammation Lung Diseases Antibodies >12 publications with BTLA and Lung Diseases Adenocarcinoma Antibodies >5 publications with BTLA and Adenocarcinoma Kidney Diseases Antibodies >4 publications with BTLA and Kidney Diseases Immunologic Deficiency Syndromes Antibodies >3 publications with BTLA and Immunologic Deficiency Syndromes Lung Neoplasms Antibodies >3 publications with BTLA and Lung Neoplasms Uterine Diseases Antibodies >2 publications with BTLA and Uterine Diseases Learning Disorders Antibodies >2 publications with BTLA and Learning Disorders Organs/Tissues associated with BTLA recombinant protein Organ/Tissue Name Pubmed Publications Blood Antibodies >160 publications with BTLA and Blood Brain Antibodies >11 publications with BTLA and Brain Lymph Node Antibodies >11 publications with BTLA and Lymph Node Thymus Antibodies >5 publications with BTLA and Thymus Kidney Antibodies >5 publications with BTLA and Kidney Pharynx Antibodies >2 publications with BTLA and Pharynx TOP © 2006-24 MyBioSource.com. 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