NP_296371.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
tumor necrosis factor ligand superfamily member 13B
NCBI Official Synonym Full Names
tumor necrosis factor (ligand) superfamily, member 13b
NCBI Official Synonym Symbols
BAFF; BLyS; TALL1; THANK; zTNF4; TALL-1; TNFSF20; D8Ertd387e [Similar Products]
NCBI Protein Information
tumor necrosis factor ligand superfamily member 13B; B-cell-activating factor; b cell-activating factor
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 13B
UniProt Synonym Protein Names
B-cell-activating factor; BAFF
UniProt Synonym Gene Names
UniProt Entry Name
TN13B_MOUSE
UniProt Comments for BAFF
BAFF: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. Belongs to the tumor necrosis factor family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytokine; Cell cycle regulation; Apoptosis; Membrane protein, integral
Cellular Component: extracellular space; membrane; perinuclear region of cytoplasm; cell; cytoplasm; plasma membrane; integral to membrane; extracellular region
Molecular Function: cytokine activity; tumor necrosis factor receptor binding
Biological Process: B cell costimulation; regulation of immune response; B cell homeostasis; immunoglobulin secretion; T cell costimulation; positive regulation of B cell proliferation; positive regulation of germinal center formation; immune response; positive regulation of T cell proliferation
Research Articles on BAFF
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Products associated with BAFF recombinant protein
Pathways associated with BAFF recombinant protein
Diseases associated with BAFF recombinant protein
Organs/Tissues associated with BAFF recombinant protein
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