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Add To Compare List Cd19 recombinant protein :: B-lymphocyte antigen CD19 (Cd19) Recombinant Protein Catalog # MBS959543 Unit / Price 0.5 mg (E-Coli) / $1,160 +1 FREE 8GB USB 0.05 mg (Baculovirus) / $1,160 +1 FREE 8GB USB 0.5 mg (Yeast) / $1,415 +1 FREE 8GB USB 0.05 mg (Mammalian-Cell) / $1,415 +1 FREE 8GB USB 1 mg (E-Coli) / $1,755 +2 FREE 8GB USB 0.1 mg (Baculovirus) / $1,755 +2 FREE 8GB USB 1 mg (Yeast) / $2,210 +2 FREE 8GB USB 0.1 mg (Mammalian-Cell) / $2,210 +2 FREE 8GB USB 0.5 mg (Baculovirus) / $2,210 +2 FREE 8GB USB 1 mg (Baculovirus) / $3,345 +4 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name B-lymphocyte antigen CD19 (Cd19), Recombinant Protein Full Product Name Recombinant Mouse B-lymphocyte antigen CD19 (Cd19) Product Synonym Names B-lymphocyte antigen CD19; Differentiation antigen CD19; CD_antigen=; CD19 Product Gene Name Cd19 recombinant protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 19-287, partial, provide the complete extracellular domain. Sequence RPQKSLLVEV EEGGNVVLPC LPDSSPVSSE KLAWYRGNQS TPFLELSPGS PGLGLHVGSL GILLVIVNVS DHMGGFYLCQ KRPPFKDIWQ PAWTVNVEDS GEMFRWNASD VRDLDCDLRN RSSGSHRSTS GSQLYVWAKD HPKVWGTKPV CAPRGSSLNQ SLINQDLTVA PGSTLWLSCG VPPVPVAKGS ISWTHVHPRR PNVSLLSLSL GGEHPVREMW VWGSLLLLPQ ATALDEGTYY CLRGNLTIER HVKVIARSAV WLWLLRTGG 3D Structure ModBase 3D Structure for P25918 Host E Coli or Yeast or Baculovirus or Mammalian Cell Purity/Purification Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific) Form/Format Lyophilized or liquid (Format to be determined during the manufacturing process) Tag Information This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information. Sterility Sterile filter available upon request. Endotoxin Low endotoxin available upon request. Species Mus musculus (Mouse) Preparation and Storage Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of Cd19 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP NCBI/Uniprot data below describe general gene information for Cd19. It may not necessarily be applicable to this product. NCBI GI # 146149173 NCBI GeneID 12478 NCBI Accession # NP_033974.2 [Other Products] NCBI GenBank Nucleotide # NM_009844.2 [Other Products] UniProt Primary Accession # P25918 [Other Products] UniProt Secondary Accession # Q542B2[Other Products] UniProt Related Accession # P25918[Other Products] Molecular Weight 60,149 Da TOP NCBI Official Full Name B-lymphocyte antigen CD19 NCBI Official Synonym Full Names CD19 antigen NCBI Official Symbol Cd19 [Similar Products] NCBI Official Synonym Symbols AW495831 [Similar Products] NCBI Protein Information B-lymphocyte antigen CD19; differentiation antigen CD19 UniProt Protein Name B-lymphocyte antigen CD19 UniProt Synonym Protein Names Differentiation antigen CD19; CD_antigen: CD19 Protein Family B-lymphocyte antigen UniProt Gene Name Cd19 [Similar Products] UniProt Entry Name CD19_MOUSE TOP TOP UniProt Comments for Cd19 CD19: a cell surface molecule which assembles with the antigen receptor of B lymphocytes. A critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation. Ligation increases intracellular calcium levels and decreases the threshold for antigen receptor signaling. Germinal center formation is significantly reduced in CD19-deficient mice. Protein type: Membrane protein, integral; Cell surfaceCellular Component: protein complex; membrane; integral to membrane; external side of plasma membraneBiological Process: B cell receptor signaling pathway; positive regulation of release of sequestered calcium ion into cytosol Research Articles on Cd19 1. This inhibitory function of FcgammaRIIB in impairing the spatial-temporal colocalization of BCR and CD19 microclusters in the B cell immunological synapse may help explain the hyper-reactive features of systemic lupus erythematosus TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with Cd19 recombinant protein Reference Product PubMed Publications Cd5 recombinant protein >1038 publications with Cd19 and Cd5 Cd79a recombinant protein >149 publications with Cd19 and Cd79a Cd79b recombinant protein >106 publications with Cd19 and Cd79b Cd81 recombinant protein >96 publications with Cd19 and Cd81 Cr2 recombinant protein >75 publications with Cd19 and Cr2 Lyn recombinant protein >56 publications with Cd19 and Lyn Btk recombinant protein >40 publications with Cd19 and Btk Vav1 recombinant protein >13 publications with Cd19 and Vav1 Pik3r1 recombinant protein >2 publications with Cd19 and Pik3r1 Pathways associated with Cd19 recombinant protein Products by Pathway Pathway Diagram Adaptive Immune System Pathway antibodies Adaptive Immune System Pathway Diagram Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway antibodies Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway Diagram B Cell Receptor Signaling Pathway antibodies B Cell Receptor Signaling Pathway Diagram B Cell Receptor Signaling Pathway antibodies B Cell Receptor Signaling Pathway Diagram B Cell Receptor Signaling Pathway antibodies B Cell Receptor Signaling Pathway Diagram Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram DAP12 Interactions Pathway antibodies DAP12 Interactions Pathway Diagram DAP12 Signaling Pathway antibodies DAP12 Signaling Pathway Diagram Disease Pathway antibodies Disease Pathway Diagram Downstream Signal Transduction Pathway antibodies Downstream Signal Transduction Pathway Diagram Diseases associated with Cd19 recombinant protein Disease Name Pubmed Publications Cardiovascular Diseases Antibodies >430 publications with Cd19 and Cardiovascular Diseases Inflammation Antibodies >344 publications with Cd19 and Inflammation Respiratory Tract Diseases Antibodies >321 publications with Cd19 and Respiratory Tract Diseases Neoplasms, Experimental Antibodies >318 publications with Cd19 and Neoplasms, Experimental Necrosis Antibodies >313 publications with Cd19 and Necrosis Lung Diseases Antibodies >201 publications with Cd19 and Lung Diseases Liver Diseases Antibodies >161 publications with Cd19 and Liver Diseases Cell Transformation, Neoplastic Antibodies >135 publications with Cd19 and Cell Transformation, Neoplastic Respiratory Tract Infections Antibodies >108 publications with Cd19 and Respiratory Tract Infections Asthma Antibodies >92 publications with Cd19 and Asthma Organs/Tissues associated with Cd19 recombinant protein Organ/Tissue Name Pubmed Publications Blood Antibodies >5312 publications with Cd19 and Blood Bone Marrow Antibodies >1505 publications with Cd19 and Bone Marrow Spleen Antibodies >471 publications with Cd19 and Spleen Lymph Node Antibodies >410 publications with Cd19 and Lymph Node Lymph Antibodies >365 publications with Cd19 and Lymph Lung Antibodies >183 publications with Cd19 and Lung Thymus Antibodies >161 publications with Cd19 and Thymus Tonsil Antibodies >108 publications with Cd19 and Tonsil Brain Antibodies >95 publications with Cd19 and Brain Intestine Antibodies >90 publications with Cd19 and Intestine TOP © 2006-24 MyBioSource.com. 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