NP_001189368.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28.1 kDa
NCBI Official Full Name
natural cytotoxicity triggering receptor 3 ligand 1
NCBI Official Synonym Full Names
natural killer cell cytotoxicity receptor 3 ligand 1
NCBI Protein Information
natural cytotoxicity triggering receptor 3 ligand 1
UniProt Protein Name
Natural cytotoxicity triggering receptor 3 ligand 1
UniProt Synonym Protein Names
B7 homolog 6; B7-H6
UniProt Synonym Gene Names
NCBI Summary for B7-H6 / B7H6
B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]
UniProt Comments for B7-H6 / B7H6
B7-H6: Triggers NCR3-dependent natural killer cell activation.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 11p15.1
Cellular Component: plasma membrane
Biological Process: regulation of immune response
Research Articles on B7-H6 / B7H6
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Products associated with B7-H6 / B7H6 active protein
Pathways associated with B7-H6 / B7H6 active protein
Diseases associated with B7-H6 / B7H6 active protein
Organs/Tissues associated with B7-H6 / B7H6 active protein
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