NP_061131.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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NCBI Official Full Name
beta-defensin 103
UniProt Protein Name
Beta-defensin 103
UniProt Synonym Protein Names
Beta-defensin 3; BD-3; DEFB-3; HBD3; hBD-3; Defensin, beta 103; Defensin-like protein
UniProt Synonym Gene Names
UniProt Entry Name
D103A_HUMAN
UniProt Comments for BD-3
defensin, beta 3: Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. Belongs to the beta-defensin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 8p23.1
Cellular Component: Golgi lumen; extracellular region
Biological Process: defense response to bacterium; innate immune response; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria
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Pathways associated with BD-3 recombinant protein
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