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BDNF recombinant protein

Scan QR to view Datasheet Catalog #    MBS538322 BDNF recombinant protein
Unit / Price
0.002 mg  /  $180 +1 FREE 8GB USB
0.01 mg  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BDNF, Recombinant Protein

 Also Known As   

BDNF protein

 Product Synonym Names    Brain Derived Neurotrophic Factor protein
 Product Gene Name   

BDNF recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    Region of BDNF protein correspond ing to amino acids MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR .
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 Host    Human
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 Purity/Purification    > 98% pure
 Form/Format    Lyophilized from 20 mM Sodium Citrate buffer, pH 5.0. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml.
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 Protein Type    Recombinant
 Biological Significance    BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/tr kb. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues.
 Bioactivity    Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 ug/ml.
 Endotoxin Levels    Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
 Expression System    E Coli
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 Preparation and Storage    Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of BDNF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for BDNF recombinant protein

   Purified recombinant Human BDNF protein
 Product Categories/Family for BDNF recombinant protein    Cytokines & Growth Factors
 Applications Tested/Suitable for BDNF recombinant protein   

User optimized

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NCBI/Uniprot data below describe general gene information for BDNF. It may not necessarily be applicable to this product.
 NCBI GI #    146262023
 NCBI GeneID    100048914
 NCBI Accession #    NP_001078951.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001085482.1 [Other Products]
 Molecular Weight    27.0 kDa
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 NCBI Official Full Name    brain-derived neurotrophic factor
 NCBI Official Synonym Full Names    brain-derived neurotrophic factor<
 NCBI Official Symbol    bdnf-b [Similar Products]
 NCBI Official Synonym Symbols   
bdnf
[Similar Products]
 NCBI Protein Information    brain-derived neurotrophic factor
 Protein Family    BDNF/NT-3 growth factors receptor
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 Research Articles on BDNF    1. activity-dependent conversion of proBDNF to mBDNF may regulate synapse elimination.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with BDNF recombinant protein
 Products by Pathway  Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
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