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Adrb2 recombinant protein :: Beta-2 adrenergic receptor (Adrb2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS962378
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 Product Name   

Beta-2 adrenergic receptor (Adrb2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Rat Beta-2 adrenergic receptor (Adrb2)

 Product Synonym Names    Recombinant Beta-2 adrenergic receptor (Adrb2); Beta-2 adrenergic receptor; Beta-2 adrenoreceptor; Beta-2 adrenoceptor
 Product Gene Name   

Adrb2 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Adrb2; Adrb2r [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    330-418
 Chromosome Location    Chromosome: 18; NC_005117.3 (56739990..56742032, complement). Location: 18q12.1
 3D Structure    ModBase 3D Structure for P10608
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90%(SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rattus norvegicus (Rat)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C. Note: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Adrb2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Adrb2 recombinant protein

   Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
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 SDS-PAGE of Adrb2 recombinant protein    Adrb2 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Adrb2. It may not necessarily be applicable to this product.
 NCBI GI #    114768
 NCBI GeneID    24176
 NCBI Accession #    P10608.1 [Other Products]
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 UniProt Primary Accession #    P10608 [Other Products]
 UniProt Secondary Accession #    Q6LCR3 [Other Products]
 UniProt Related Accession #    P10608 [Other Products]
 Molecular Weight    27kD [Similar Products]
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 NCBI Official Full Name    Beta-2 adrenergic receptor
 NCBI Official Synonym Full Names    adrenoceptor beta 2, surface
 NCBI Official Symbol    Adrb2 [Similar Products]
 NCBI Protein Information    beta-2 adrenergic receptor; beta-2 adrenoceptor; beta-2 adrenoreceptor; adrenergic receptor, beta 2; Adrenergic beta 2- receptor surface; adrenergic, beta-2-, receptor, surface
 UniProt Protein Name    Beta-2 adrenergic receptor
 UniProt Synonym Protein Names   
Beta-2 adrenoreceptor
 Protein Family    Beta-2 adrenergic receptor
 UniProt Gene Name    Adrb2 [Similar Products]
 UniProt Synonym Gene Names    Adrb2r; Beta-2 adrenoceptor [Similar Products]
 UniProt Entry Name    ADRB2_RAT
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 NCBI Summary for Adrb2    binds adrenergic receptor agonist zinterol; plays a role in G-protein coupled receptor regulation of calcium channel current [RGD, Feb 2006]
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 UniProt Comments for Adrb2    ADRB2: Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.

Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass

Cellular Component: intracellular membrane-bound organelle; integral to plasma membrane; dendrite; integral to membrane; dendritic spine; caveola; membrane; axon; apical plasma membrane; cytoplasm; plasma membrane; nucleus; endosome; sarcolemma; receptor complex

Molecular Function: protein homodimerization activity; G-protein alpha-subunit binding; norepinephrine binding; drug binding; epinephrine binding; PDZ domain binding; ionotropic glutamate receptor binding; protein binding; potassium channel regulator activity; enzyme binding; protein complex binding; dopamine binding; beta2-adrenergic receptor activity; B2 bradykinin receptor binding; adenylate cyclase binding

Biological Process: diet induced thermogenesis; wound healing; positive regulation of apoptosis; regulation of vasodilation; positive regulation of potassium ion transport; regulation of systemic arterial blood pressure by norepinephrine-epinephrine; female pregnancy; positive regulation of vasodilation; G-protein signaling, adenylate cyclase activating pathway; positive regulation of MAPKKK cascade; diaphragm contraction; negative regulation of smooth muscle contraction; positive regulation of cell proliferation; negative regulation of ossification; associative learning; aging; bone resorption; arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway; regulation of smooth muscle contraction; synaptic transmission, glutamatergic; receptor-mediated endocytosis; negative regulation of multicellular organism growth; adenylate cyclase activation; regulation of calcium ion transport; response to testosterone stimulus; regulation of sodium ion transport; liver development; positive regulation of bone mineralization; G-protein coupled receptor protein signaling pathway; negative regulation of angiogenesis; positive regulation of the force of heart contraction by epinephrine; positive regulation of ATPase activity; response to estrogen stimulus; positive regulation of protein ubiquitination; negative regulation of inflammatory response; heat generation; brown fat cell differentiation; response to hypoxia; positive regulation of transcription from RNA polymerase II promoter; response to cold; regulation of sensory perception of pain; response to progesterone stimulus; positive regulation of skeletal muscle growth; regulation of excitatory postsynaptic membrane potential; positive regulation of heart contraction; norepinephrine-epinephrine vasodilation involved in regulation of systemic arterial blood pressure
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 Research Articles on Adrb2    1. Regulation of ventricular contractility is not the primary function of the beta2-AR; rather, beta2-AR could function to activate protein kinase B and AMP-activated protein kinase signaling, modulating muscle mass and energetic metabolism of ventricular muscle.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Adrb2 recombinant proteinPathways associated with Adrb2 recombinant protein
 Reference Product  PubMed Publications
 Nsf recombinant protein  >4 publications with Adrb2 and Nsf
 Products by Pathway  Pathway Diagram
 Adrenoceptors Pathway antibodies  Adrenoceptors Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 CFTR Activity In The Plasma Membrane Pathway antibodies  CFTR Activity In The Plasma Membrane Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
Organs/Tissues associated with Adrb2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >730 publications with Adrb2 and Lung
 Prostate Antibodies  >27 publications with Adrb2 and Prostate
 Testis Antibodies  >17 publications with Adrb2 and Testis
 Cervix Antibodies  >5 publications with Adrb2 and Cervix
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