NP_000016.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
beta-3 adrenergic receptor
NCBI Official Synonym Full Names
adrenoceptor beta 3
NCBI Official Synonym Symbols
NCBI Protein Information
beta-3 adrenergic receptor; beta-3 adrenoceptor; beta-3 adrenoreceptor; adrenergic, beta-3-, receptor
UniProt Protein Name
Beta-3 adrenergic receptor
UniProt Synonym Protein Names
Beta-3 adrenoreceptor
UniProt Synonym Gene Names
UniProt Entry Name
ADRB3_HUMAN
NCBI Summary for ADRB3
The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. [provided by RefSeq, Feb 2009]
UniProt Comments for ADRB3
Function: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Expressed mainly in adipose tissues.
Polymorphism: The variant Arg-64 seems to be associated with weight gain (obesity) and is also associated with susceptibility to non-insulin-dependent diabetes mellitus (NIDDM).
Sequence similarities: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
Research Articles on ADRB3
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Products associated with ADRB3 recombinant protein
Pathways associated with ADRB3 recombinant protein
Diseases associated with ADRB3 recombinant protein
Organs/Tissues associated with ADRB3 recombinant protein
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