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BD 3 recombinant protein :: Beta Defensin -3 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS142337 BD 3 recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $1,415 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Beta Defensin -3 (BD 3), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Beta Defensin -3

 Product Synonym Names    BD 3 Human; Beta Defensin-3 Human Recombinant; HBD3; HBP3; DEFB3; HBD-3; HBP-3; DEFB103
 Product Gene Name   

BD 3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
 OMIM    606611
 3D Structure    ModBase 3D Structure for P81534
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 Host    E Coli
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 Purity/Purification    Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
 Form/Format    The HBD-3 was lyophilized without additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
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 Solubility    It is recommended to reconstitute the lyophilized Beta Defensin-3 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
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 Preparation and Storage    Lyophilized Beta Defensin-3 Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution BD-3 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.
 Other Notes    Small volumes of BD 3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for BD 3 recombinant protein

   Description: Beta Defensin-3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 45 amino acids and having a molecular mass of 5161.2 Dalton. The BD-3 is purified by proprietary chromatographic techniques.

Introduction: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103A, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.
 Product Categories/Family for BD 3 recombinant protein    CYTOKINES AND GROWTH FACTORS; Cytokines; Beta Defensin
NCBI/Uniprot data below describe general gene information for BD 3. It may not necessarily be applicable to this product.
 NCBI GI #    125656159
 NCBI GeneID    414325
 NCBI Accession #    NP_001075020.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001081551.3 [Other Products]
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 UniProt Primary Accession #    P81534 [Other Products]
 UniProt Secondary Accession #    Q8NFG6; Q9NPF6 [Other Products]
 UniProt Related Accession #    P81534 [Other Products]
 Molecular Weight    7,697 Da
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 NCBI Official Full Name    beta-defensin 103
 NCBI Official Synonym Full Names    defensin, beta 103A
 NCBI Official Symbol    DEFB103A [Similar Products]
 NCBI Official Synonym Symbols   
BD-3; HBD3; HBP3; DEFB3; HBP-3; hBD-3; DEFB-3; DEFB103
[Similar Products]
 NCBI Protein Information    beta-defensin 103; beta defensin 3; beta defensin-3; beta-defensin 3; defensin, beta 103; defensin, beta 3; defensin-like protein
 UniProt Protein Name    Beta-defensin 103
 UniProt Synonym Protein Names   
Beta-defensin 3; BD-3; DEFB-3; HBD3; hBD-3; Defensin, beta 103; Defensin-like protein
 UniProt Gene Name    DEFB103A [Similar Products]
 UniProt Synonym Gene Names    BD3; DEFB103; DEFB3; BD-3; DEFB-3; HBD3; hBD-3 [Similar Products]
 UniProt Entry Name    D103A_HUMAN
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 NCBI Summary for BD 3    Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103, an antibiotic peptide which is induced by bacteria and interferon gamma, and which displays antimicrobial activity against S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans. [provided by RefSeq, Oct 2014]
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 UniProt Comments for BD 3    defensin, beta 3: Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. Belongs to the beta-defensin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: Golgi lumen; extracellular region

Biological Process: defense response to bacterium; innate immune response; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria
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 Research Articles on BD 3    1. The encoded peptide displays antimicrobial activity against S. aureus and E. faecium.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BD 3 recombinant proteinPathways associated with BD 3 recombinant protein
 Reference Product  PubMed Publications
 CAMP recombinant protein  >2 publications with BD 3 and CAMP
 DEFB104A recombinant protein  >2 publications with BD 3 and DEFB104A
 Products by Pathway  Pathway Diagram
 Beta Defensins Pathway antibodies  Beta Defensins Pathway Diagram
 Defensins Pathway antibodies  Defensins Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
Diseases associated with BD 3 recombinant protein
 Disease Name  Pubmed Publications
 Metabolic Diseases Antibodies  >1 publications with BD 3 and Metabolic Diseases
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