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CRYBA1 recombinant protein :: Beta-crystallin A3 (CRYBA1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS966525 CRYBA1 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $965 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $965 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,190 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,190 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,450 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,450 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,915 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,915 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Beta-crystallin A3 (CRYBA1), Recombinant Protein

 Also Known As   

Recombinant Human Beta-crystallin A3 (CRYBA1)

 Product Synonym Names    Beta-crystallin A3Cleaved into the following 3 chains:; 1. Beta-crystallin A3, isoform A1, Delta4 form; 2. Beta-crystallin A3, isoform A1, Delta7 form; 3. Beta-crystallin A3, isoform A1, Delta8 form
 Product Gene Name   

CRYBA1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    CRYBA1; CRYB1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-215
 Sequence    METQAEQQEL ETLPTTKMAQ TNPTPGSLGP WKITIYDQEN FQGKRMEFTS SCPNVSERSF DNVRSLKVES GAWIGYEHTS FCGQQFILER GEYPRWDAWS GSNAYHIERL MSFRPICSAN HKESKMTIFE KENFIGRQWE ISDDYPSLQA MGWFNNEVGS MKIQSGAWVC YQYPGYRGYQ YILECDHHGG DYKHWREWGS HAQTSQIQSI RRIQQ
 OMIM    gene 600881
 3D Structure    ModBase 3D Structure for P05813
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CRYBA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for CRYBA1 recombinant protein

   CRYBA1; CRYB1
NCBI/Uniprot data below describe general gene information for CRYBA1. It may not necessarily be applicable to this product.
 NCBI GI #    12056461
 NCBI GeneID    1411
 NCBI Accession #    NP_005199.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005208.4 [Other Products]
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 UniProt Primary Accession #    P05813 [Other Products]
 UniProt Secondary Accession #    Q13633; Q14CM9 [Other Products]
 UniProt Related Accession #    P05813 [Other Products]
 Molecular Weight    23,191 Da
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 NCBI Official Full Name    beta-crystallin A3
 NCBI Official Synonym Full Names    crystallin, beta A1
 NCBI Official Symbol    CRYBA1 [Similar Products]
 NCBI Official Synonym Symbols   
CRYB1; CTRCT10
[Similar Products]
 NCBI Protein Information    beta-crystallin A3; crystallin, beta A3; eye lens structural protein
 UniProt Protein Name    Beta-crystallin A3
 Protein Family    Beta-crystallin
 UniProt Gene Name    CRYBA1 [Similar Products]
 UniProt Synonym Gene Names    CRYB1 [Similar Products]
 UniProt Entry Name    CRBA1_HUMAN
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 NCBI Summary for CRYBA1    Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CRYBA1    CRYBA1: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Defects are the cause of congenital zonular cataract with sutural opacities. Two splice-variant isoforms have been described.

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; protein homodimerization activity; structural constituent of eye lens

Biological Process: lens development in camera-type eye; visual perception

Disease: Cataract 10, Multiple Types
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 Research Articles on CRYBA1    1. A novel splice site mutation in CRYBA1/A3 is associated with autosomal dominant nuclear cataracts in a Chinese family.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CRYBA1 recombinant proteinDiseases associated with CRYBA1 recombinant protein
 Reference Product  PubMed Publications
 CRYBB2 recombinant protein  >19 publications with CRYBA1 and CRYBB2
 CRYBB1 recombinant protein  >18 publications with CRYBA1 and CRYBB1
 CRYAA recombinant protein  >14 publications with CRYBA1 and CRYAA
 CRYBB3 recombinant protein  >12 publications with CRYBA1 and CRYBB3
 CRYAB recombinant protein  >12 publications with CRYBA1 and CRYAB
 GJA8 recombinant protein  >10 publications with CRYBA1 and GJA8
 GJA3 recombinant protein  >8 publications with CRYBA1 and GJA3
 BFSP2 recombinant protein  >5 publications with CRYBA1 and BFSP2
 PITX3 recombinant protein  >2 publications with CRYBA1 and PITX3
 TMEM114 recombinant protein  >1 publications with CRYBA1 and TMEM114
 Disease Name  Pubmed Publications
 Cataract, Congenital Zonular, with Sutural Opacities Antibodies  >2 publications with CRYBA1 and Cataract, Congenital Zonular, with Sutural Opacities
 Infertility, Male Antibodies  >1 publications with CRYBA1 and Infertility, Male
 Carcinoma Antibodies  >1 publications with CRYBA1 and Carcinoma
 Cardiovascular Diseases Antibodies  >1 publications with CRYBA1 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >1 publications with CRYBA1 and Nervous System Diseases
 Inflammation Antibodies  >1 publications with CRYBA1 and Inflammation
 Hypertension Antibodies  >1 publications with CRYBA1 and Hypertension
 Nerve Degeneration Antibodies  >1 publications with CRYBA1 and Nerve Degeneration
 Weight Loss Antibodies  >1 publications with CRYBA1 and Weight Loss
Organs/Tissues associated with CRYBA1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >44 publications with CRYBA1 and Eye
 Skin Antibodies  >2 publications with CRYBA1 and Skin
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