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BST1 recombinant protein :: Bone Marrow Stromal Cell Antigen 1 (BST1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2010989 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $135 +1 FREE 8GB USB
0.05 mg  /  $245 +1 FREE 8GB USB
0.1 mg  /  $365 +1 FREE 8GB USB
0.2 mg  /  $450 +1 FREE 8GB USB
0.5 mg  /  $870 +1 FREE 8GB USB
1 mg  /  $1,280 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Bone Marrow Stromal Cell Antigen 1 (BST1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Bone Marrow Stromal Cell Antigen 1 (BST1)

 Product Gene Name   

BST1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.
 Chromosome Location    Chromosome: 4; NC_000004.11 (15704573..15741121). Location: 4p15
 OMIM    600387
 3D Structure    ModBase 3D Structure for Q10588
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
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 Organism    Homo sapiens (Human)
 Expression System    Prokaryotic expression
 Residues    Arg63~Ala313 (Accession # Q10588) with two N-terminal Tags, His-tag and T7-tag
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of BST1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for BST1 recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for BST1 recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-PAGE of BST1 recombinant protein    BST1 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for BST1. It may not necessarily be applicable to this product.
 NCBI GI #    168229159
 NCBI GeneID    683
 NCBI Accession #    NP_004325.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004334.2 [Other Products]
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 UniProt Primary Accession #    Q10588 [Other Products]
 UniProt Secondary Accession #    Q5U0K0; Q96EN3; B2R6A2 [Other Products]
 UniProt Related Accession #    Q10588 [Other Products]
 Molecular Weight    32.3kDa
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 NCBI Official Full Name    ADP-ribosyl cyclase 2
 NCBI Official Synonym Full Names    bone marrow stromal cell antigen 1
 NCBI Official Symbol    BST1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    ADP-ribosyl cyclase 2; BST-1; cADPr hydrolase 2; NAD(+) nucleosidase; bone marrow stromal antigen 1; cyclic ADP-ribose hydrolase 2
 UniProt Protein Name    ADP-ribosyl cyclase 2
 UniProt Synonym Protein Names   
Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2
 Protein Family    GPI inositol-deacylase
 UniProt Gene Name    BST1 [Similar Products]
 UniProt Synonym Gene Names    BST-1 [Similar Products]
 UniProt Entry Name    BST1_HUMAN
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 NCBI Summary for BST1    Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BST1    BST1: Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. Belongs to the ADP-ribosyl cyclase family.

Protein type: Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC; Hydrolase; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 4p15

Cellular Component: extrinsic to membrane; plasma membrane

Molecular Function: transferase activity; phosphorus-oxygen lyase activity; NAD+ nucleosidase activity; NAD(P)+ nucleosidase activity

Biological Process: metabolic process; multicellular organismal development; positive regulation of B cell proliferation; humoral immune response
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 Research Articles on BST1    1. BST1 SNPs rs11931532, rs12645693, & rs11724635 did not correlate with sporadic PD. The relationship of rs11724635 & sporadic PD had borderline significance. Smoking or caffeine intake did not correlate with SNP rs11724635 affecting sporadic PD.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BST1 recombinant proteinPathways associated with BST1 recombinant protein
 Reference Product  PubMed Publications
 CD38 recombinant protein  >1 publications with BST1 and CD38
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Nicotinate And Nicotinamide Metabolism Pathway antibodies  Nicotinate And Nicotinamide Metabolism Pathway Diagram
 Nicotinate And Nicotinamide Metabolism Pathway antibodies  Nicotinate And Nicotinamide Metabolism Pathway Diagram
 Pancreatic Secretion Pathway antibodies  Pancreatic Secretion Pathway Diagram
 Pancreatic Secretion Pathway antibodies  Pancreatic Secretion Pathway Diagram
 Salivary Secretion Pathway antibodies  Salivary Secretion Pathway Diagram
 Salivary Secretion Pathway antibodies  Salivary Secretion Pathway Diagram
Diseases associated with BST1 recombinant proteinOrgans/Tissues associated with BST1 recombinant protein
 Disease Name  Pubmed Publications
 Parkinson Disease Antibodies  >19 publications with BST1 and Parkinson Disease
 Nervous System Diseases Antibodies  >15 publications with BST1 and Nervous System Diseases
 Lung Neoplasms Antibodies  >1 publications with BST1 and Lung Neoplasms
 Immune System Diseases Antibodies  >1 publications with BST1 and Immune System Diseases
 Cardiovascular Diseases Antibodies  >1 publications with BST1 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >1 publications with BST1 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with BST1 and Brain
 Bone Marrow Antibodies  >5 publications with BST1 and Bone Marrow
 Blood Antibodies  >2 publications with BST1 and Blood
 Muscle Antibodies  >1 publications with BST1 and Muscle
 Prostate Antibodies  >1 publications with BST1 and Prostate
 Intestine Antibodies  >1 publications with BST1 and Intestine
 Lung Antibodies  >1 publications with BST1 and Lung
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