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BDNF recombinant protein :: Brain Derived Neurotrophic Factor (BDNF) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2009541 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
SDS-PAGE
Unit / Price
0.01 mg  /  $150 +1 FREE 8GB USB
0.05 mg  /  $290 +1 FREE 8GB USB
0.1 mg  /  $455 +1 FREE 8GB USB
0.2 mg  /  $560 +1 FREE 8GB USB
0.5 mg  /  $1,080 +1 FREE 8GB USB
1 mg  /  $1,610 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Brain Derived Neurotrophic Factor (BDNF), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Brain Derived Neurotrophic Factor (BDNF)

 Product Gene Name   

BDNF recombinant protein

[Similar Products]
 Matching Pairs    Antibody: Brain Derived Neurotrophic Factor (BDNF) (MBS2003494)
Antigen: Brain Derived Neurotrophic Factor (BDNF) (MBS2009541)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF- NYLD AANMSMRVRR HSDPARRGEL SVCDSISEWV TAADKKTAVD MSGGTVTVLE KVPVSKGQLK QYFYETKCNP MGYTKEGCRG IDKRHWNSQC RTTQSYVRAL TMDSKKRIGW RFIRIDTSCV CTLTIKRG
 Chromosome Location    Chromosome: 3; NC_005102.3 (107371329..107421908). Location: 3q33
 3D Structure    ModBase 3D Structure for P23363
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
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 Organism    Rattus norvegicus (Rat)
 Expression System    Prokaryotic expression
 Residues    Asn117~Gly248 (Accession # P23363) with N-terminal His-Tag
 Subcellular Location    Secreted
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Predicted Isoelectric Point    9.6
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of BDNF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for BDNF recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for BDNF recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-PAGE of BDNF recombinant protein    BDNF recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for BDNF. It may not necessarily be applicable to this product.
 NCBI GI #    397174764
 NCBI GeneID    24225
 NCBI Accession #    NP_001257559.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001270630.1 [Other Products]
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 UniProt Primary Accession #    P23363 [Other Products]
 UniProt Secondary Accession #    Q53YL8 [Other Products]
 UniProt Related Accession #    P23363 [Other Products]
 Molecular Weight    16.6kDa
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 NCBI Official Full Name    brain-derived neurotrophic factor isoform 1
 NCBI Official Synonym Full Names    brain-derived neurotrophic factor
 NCBI Official Symbol    Bdnf [Similar Products]
 NCBI Protein Information    brain-derived neurotrophic factor; brain derived neurotrophic factor; brain derived neurothrophic factor
 UniProt Protein Name    Brain-derived neurotrophic factor
 Protein Family    Brain-derived neurotrophic factor
 UniProt Gene Name    Bdnf [Similar Products]
 UniProt Synonym Gene Names    BDNF [Similar Products]
 UniProt Entry Name    BDNF_RAT
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 NCBI Summary for BDNF    plays a role in the development of hippocampal long term potentiation; involved in regulation of synaptic plasticity [RGD, Feb 2006]
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 UniProt Comments for BDNF    Function: During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS

By similarity.

Subunit structure: Monomers and homodimers. Binds to NTRK2/TRKB

By similarity.

Subcellular location: Secreted.

Post-translational modification: Converted into mature BDNF by plasmin (PLG)

By similarity.

Sequence similarities: Belongs to the NGF-beta family.
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 Research Articles on BDNF    1. BDNF plays a locally crucial role in pain-related behavior development following inferior alveolar nerve injury.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with BDNF recombinant proteinDiseases associated with BDNF recombinant protein
 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Activation Of TRKA Receptors Pathway antibodies  Activation Of TRKA Receptors Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Brain Derived Neurotrophic Factor Pathway antibodies  Brain Derived Neurotrophic Factor Pathway Diagram
 Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies  Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Frs2-mediated Activation Pathway antibodies  Frs2-mediated Activation Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3318 publications with BDNF and Nervous System Diseases
 Brain Injuries Antibodies  >788 publications with BDNF and Brain Injuries
 Depressive Disorder Antibodies  >573 publications with BDNF and Depressive Disorder
 Nerve Degeneration Antibodies  >519 publications with BDNF and Nerve Degeneration
 Schizophrenia Antibodies  >512 publications with BDNF and Schizophrenia
 Brain Ischemia Antibodies  >501 publications with BDNF and Brain Ischemia
 Body Weight Antibodies  >486 publications with BDNF and Body Weight
 Cognition Disorders Antibodies  >477 publications with BDNF and Cognition Disorders
 Inflammation Antibodies  >470 publications with BDNF and Inflammation
 Movement Disorders Antibodies  >465 publications with BDNF and Movement Disorders
Organs/Tissues associated with BDNF recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >12865 publications with BDNF and Brain
 Dorsal Root Ganglion Antibodies  >427 publications with BDNF and Dorsal Root Ganglion
 Inner Ear Antibodies  >250 publications with BDNF and Inner Ear
 Lung Antibodies  >111 publications with BDNF and Lung
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